1.

Record Nr.

UNINA9910789251703321

Autore

Silverman Richard B.

Titolo

The organic chemistry of drug design and drug action / / Richard B. Silverman, Mark W. Holladay

Pubbl/distr/stampa

Amsterdam : , : Elsevier, , [2014]

©2014

ISBN

0-12-382031-6

Edizione

[Third edition.]

Descrizione fisica

1 online resource (xviii, 517 pages ) : illustrations (some color)

Disciplina

615.1/9

Soggetti

Pharmaceutical chemistry

Bioorganic chemistry

Molecular pharmacology

Drugs - Design

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Bibliographic Level Mode of Issuance: Monograph

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Introduction -- Lead discovery and lead modification -- Receptors -- Enzymes -- Enzyme inhibition and inactivation -- Dna-interactive agents -- Drug resistance and drug synergism -- Drug metabolism -- Prodrugs and drug delivery systems.