1.

Record Nr.

UNISA990005592540203316

Titolo

Similarity in language, thought and perception / edited by Cristina Cacciari : contributors Dedre Gentner ... [et al.]

Pubbl/distr/stampa

Turnhout : Brepols, 1995

Descrizione fisica

157 p. ; 24 cm

Collana

Semiotic and cognitive studies / series editors Umberto Eco e Patrizia Violi ; 1

Disciplina

153

Soggetti

SEMIOTICA - STUDI

Percezione

Argomentazione - Ruolo [dell'] Analogia

Ragionamento - Analogia

SEGNI - PERCEZIONE

CONGRESSI - SAN MARINO - 1991

Collocazione

BB 153 SIM

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Interventi presentati nel corso del workshop tenuto all'International center for Semiotic and Cognitive studies di San Marino nel 1991.



2.

Record Nr.

UNINA9910460918103321

Titolo

Advanced vaccine research : methods for the decade of vaccines / / edited by Fabio Bagnoli and Rino Rappuoli

Pubbl/distr/stampa

Norfolk, England : , : Caister Academic Press, , [2015]

©2015

ISBN

1-910190-04-7

Descrizione fisica

1 online resource (474 p.)

Disciplina

615.372

Soggetti

Vaccines - Research

Drug development

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Contents; Contributors; Current Books of Interest; Preface; Part I: Innovative Technologies and Approaches in Vaccine Research; 1: Deep Sequencing in Vaccine Research, Development and Surveillance ; Impact of DNA sequencing on vaccines research and development; Deep sequencing potential to transform vaccinology; 2: New Bioinformatics Algorithms Applied to Deep Sequencing Projects ; Introduction; Better understating of host and pathogen genomes; Computational approaches to study adaptive immune responses; Better understanding of transcriptome

Epigenomics: understanding of inheritable chemical changesMetagenomics: finding new pathogens and strains; Bioinformatics challenges; 3: Comparative Genomics Approaches for Tracking the Emergence and Spread of Disease-associated Bacteria; Background; Comparative genomics of disease-associated bacteria; Assays for identification of disease-associated bacteria based on insights from comparative genomics; Conclusions; 4: Quantitative Proteomics in Vaccine Research; Introduction; Quantitative proteomics based on gel electrophoresis; Quantitative proteomics based on differential mass tag

Label-free technologies and targeted proteomicsMass spectrometry for viral vaccinology; Proteomic technology for vaccine development ;



Combining proteomics and system biology to improve vaccines; Concluding remarks; 5: Structural Biology in Vaccine Research; Introduction; Experimental mapping and computational prediction of epitopes; Examples of structural vaccinology for bacterial and viral pathogens; Concluding remarks and future directions; 6: Cellular Screens to Interrogate the Human T- and B-cell Repertoires and Design Better Vaccines ; Introduction

Generation of naive B- and T-cell repertoires7: Novel Strategies of Vaccine Administration: The Science Behind Epidermal and Dermal Immunization; Introduction; The skin layers; Skin antigen-presenting cells and other players in vaccination; Principles and methods in skin immunization; Vaccine formulation and immunity; Immunological advantage of epidermal and dermal immunization; 8: Toll-like Receptors as Targets to Develop Novel Adjuvants; Introduction; Innate immunity; TLR-based adjuvants in high-priority vaccines; Lessons learned from studies of TLR agonists as adjuvants

Safety considerations of TLR agonistsChallenges for the next decade; 9: The Importance of Cell-mediated Immunity for Bacterial Vaccines ; Introduction; T-cell responses to bacterial infection; Targeting cellular immunity for novel anti-bacterial vaccine design; 10: T-cell-inducing Vaccines; Introduction; How can we measure T-cell responses?; Technologies for inducing T-cell responses by vaccination; Heterologous prime-boost immunization; Successful clinical development of T-cell vaccines; 11: Exploiting the Mutanome for Personalized Cancer Immunotherapy

Cancer mutations as therapeutic targets

Sommario/riassunto

Since the publication of our first book book ""Vaccine Design: Innovative Approaches and Novel Strategies"" in 2011, the field of vaccinology has advanced significantly. The application of new sophisticated 'omics' technologies and the use of pioneering approaches have yielded a wealth of new data. This new book aims to distill the most important new findings to provide a timely overview of the field. Written by leading experts in the field, each chapter affords a critical insight to a particular topic, reviews current research, discusses future direction and aims to stimulate discussion. The



3.

Record Nr.

UNINA9910788892203321

Autore

Jech Thomas J.

Titolo

Ideals over uncountable sets : application of almost disjoint functions and generic ultrapowers / / Thomas Jech and Karel Prikry

Pubbl/distr/stampa

Providence : , : American Mathematical Society, , [1979]

©1979

ISBN

1-4704-0449-4

Descrizione fisica

1 online resource (76 p.)

Collana

Memoirs of the American Mathematical Society, , 0065-9290 ; ; volume 18, number 214 (March 1979)

Disciplina

510/.8 s

511/.3

Soggetti

Combinatorial set theory

Cardinal numbers

Ideals (Algebra)

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

"Volume 18, number 214 (second of 3 numbers)."

Nota di bibliografia

Includes bibliographical references.

Nota di contenuto

""Table of Contents""; ""0. Introduction""; ""1. Ideals over uncountable sets""; ""2. Generic ultrapowers""; ""3. Saturation of ideals and the G.C.H""; ""4. The singular cardinals problem""; ""5. Almost disjoint functions""; ""6. Applications of almost disjoint functions""; ""7. Nonregular ultrafilters and the G.C.H""