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1. |
Record Nr. |
UNINA9910788549103321 |
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Titolo |
Ethnopragmatics [[electronic resource] ] : understanding discourse in cultural context / / edited by Cliff Goddard |
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Pubbl/distr/stampa |
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Berlin ; ; New York, : Mouton de Gruyter, c2006 |
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ISBN |
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Descrizione fisica |
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1 online resource (288 p.) |
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Collana |
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Applications of cognitive linguistics, , 1861-4078 ; ; 3 |
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Classificazione |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Pragmatics - Social aspects |
Language and culture |
Semantics - Social aspects |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Front matter -- 1. Ethnopragmatics: a new paradigm / Goddard, Cliff -- 2. Anglo scripts against "putting pressure" on other people and their linguistic manifestations / Wierzbicka, Anna -- 3. "Lift your game Martina!": deadpan jocular irony and the ethnopragmatics of Australian English / Goddard, Cliff -- 4. Social hierarchy in the "speech culture" of Singapore / Wong, Jock Onn -- 5. Why the "inscrutable" Chinese face? Emotionality and facial expression in Chinese / Ye, Zhengdao -- 6. Cultural scripts: glimpses into the Japanese emotion world / Hasada, Rie -- 7. The communicative realisation of confianza and calor humano in Colombian Spanish / Travis, Catherine E. -- 8. "When I die, don't cry": the ethnopragmatics of "gratitude" in West African languages / Ameka, Felix K. -- Author index -- General index |
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Sommario/riassunto |
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The studies in this volume show how speech practices can be understood from a culture-internal perspective, in terms of values, norms and beliefs of the speech communities concerned. Focusing on examples from many different cultural locations, the contributing authors ask not only: 'What is distinctive about these particular ways of speaking?', but also: 'Why - from their own point of view - do the people concerned speak in these particular ways? What sense does it make to them?'. The ethnopragmatic approach stands in opposition to the culture-external universalist pragmatics represented by neo-Gricean pragmatics and politeness theory. Using "cultural scripts" and |
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semantic explications - techniques developed over 20 years work in cross-cultural semantics by Anna Wierzbicka and colleagues - the authors examine a wide range of phenomena, including: speech acts, terms of address, phraseological patterns, jocular irony, facial expressions, interactional routines, discourse particles, expressive derivation, and emotionality. The authors and languages are: Anna Wierzbicka (English), Cliff Goddard (Australian English), Jock Wong (Singapore English), Zhengdao Ye (Chinese), Catherine Travis (Colombian Spanish), Rie Hasada (Japanese) and Felix Ameka (Ewe). Taken together, these studies demonstrate both the profound "cultural shaping" of speech practices, and the power and subtlety of new methods and techniques of a semantically grounded ethnopragmatics. The book will appeal not only to linguists and anthropologists, but to all scholars and students with an interest in language, communication and culture. |
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2. |
Record Nr. |
UNINA9910787406103321 |
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Titolo |
Pharmaceutical amorphous solid dispersions / / edited by Ann Newman, Seventh Street Development Group Lafayette, Indiana, USA ; contributors, Patrick Augustijns [and forty seven others] |
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Pubbl/distr/stampa |
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Hoboken, New Jersey : , : Wiley, , 2015 |
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©2015 |
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ISBN |
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1-118-90141-X |
1-118-90138-X |
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Descrizione fisica |
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1 online resource (1218 p.) |
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Disciplina |
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Soggetti |
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Pharmaceutical technology |
Absorption |
Solubility |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references at the end of each chapters and index. |
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Nota di contenuto |
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Cover; Title Page; Copyright; Dedication; Preface; Contributors; 1.1 |
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Introduction; 1.2 Formation of the Amorphous State and the Glass Transition Temperature; 1.3 Structure of Amorphous Solids; 1.4 Molecular Mobility in Amorphous Solids; 1.5 Solid-State Crystallization from the Amorphous State; 1.6 Supersaturation of API in Aqueous Media from the Amorphous State; 1.7 Mixtures of Amorphous Solids; 1.8 Formation and Properties of Amorphous Solid Dispersions; 1.9 Solid-State Crystallization from Amorphous Dispersions; 1.10 Dissolution and Supersaturation of API from Amorphous Solid Dispersions |
1.11 Pharmaceutical Development of Amorphous Solid DispersionsReferences; Chapter 1: Introduction to Amorphous Solid Dispersions; 2.1 Polymers Commonly Used in Amorphous Solid Dispersions; 2.2 Surfactants Commonly Used in Solid Dispersions; 2.3 Synergies between Surfactants and Polymers in Solid Dispersion Systems; 2.4 Physical Properties of Materials and Considerations in Designing Solid Dispersions; References; Chapter 2: Polymers and Surfactants; 3.1 Introduction; 3.2 Amorphous Dispersion Screening; 3.3 Amorphous Solid Dispersion Selection; 3.4 Case Study; 3.5 Conclusions; References |
Chapter 3: Amorphous Solid Dispersion Screening4.1 Introduction; 4.2 Thermal Analysis Methods; 4.3 Dielectric Relaxation Methods; 4.4 Moisture Sorption Methods; 4.5 Vibrational Spectroscopy and Microspectroscopy; 4.6 Solid-State NMR Spectroscopy; 4.7 Other Molecular Spectroscopic Methods; 4.8 X-Ray Diffractometry; 4.9 Microscopic and Surface Analysis Methods; 4.10 Other Emerging Analytical Methods; 4.11 Computational Models; 4.12 Conclusions; Acknowledgments; References; Chapter 4: Solid-State Characterization of Amorphous Dispersions; 5.1 Introduction |
5.2 Theory of Crystallization in the Solid State5.3 Factors Impacting the Crystallization Tendency of Active Pharmaceutical Compounds; 5.4 Role of Additives in Modifying Solid-State Crystallization; 5.5 Assessment of Physical Stability; 5.6 Crystallization in Aqueous Environments; 5.7 Summary and Outlook; References; Chapter 5: Physical Stability and Crystallization Inhibition; 6.1 Solubility and Dissolution: An Overview; 6.2 Differences Between Crystalline API, Amorphous Materials, and Amorphous Dispersions as it Pertains to Solubility and Dissolution |
6.3 The Relationship of Polymer Properties with Solubility, Dissolution, and Supersaturation6.4 Solubility and Dissolution Factors to Consider for Dispersions; 6.5 Solubility and Dissolution Measurements for Amorphous Dispersions: Summary, Conclusions, and Recommendations; Acknowledgments; References; Chapter 6: Solubility and Dissolution Considerations for Amorphous Solid Dispersions; 7.1 Introduction: Translational Drug Development; 7.2 Translational Development at the Discovery Stage; 7.3 Translational Development After Discovery; 7.4 Conclusions; References |
Chapter 7: Translational Development of Amorphous Dispersions |
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Sommario/riassunto |
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Providing a roadmap from early to late stages of drug development, this book overviews amorphous solid dispersion technology - a leading platform to deliver poorly water soluble drugs, a major hurdle in today's pharmaceutical industry. Helps readers understand amorphous solid dispersions and apply techniques to particular pharmaceutical systems Covers physical and chemical properties, screening, scale-up, formulation, drug product manufacture, intellectual property, and regulatory considerations Has an appendix with structure and property information for polymers commonly used in drug developm |
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