1.

Record Nr.

UNINA9910227346303321

Autore

William C. Cho

Titolo

Molecular Diagnostics in the Detection of Neurodegenerative Disorders

Pubbl/distr/stampa

Frontiers Media SA, 2017

Descrizione fisica

1 electronic resource (90 p.)

Collana

Frontiers Research Topics

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

Neurodegeneration is characterized by the progressive loss of neural tissue that result in various neurodegeneration-initiated cerebral failures and complex diseases such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease. All these medical conditions are accompanied by the disruption of blood-brain barrier (BBB). The BBB is an interface, separating the brain from the circulatory system and protecting the central nervous system from potentially harmful chemicals while regulating transport of essential molecules and maintaining a stable environment. Owing to the inability of the neurons to regenerate on their own after neurodegeneration or severe damage to the neural tissue, neurodegenerative disorders do not have natural cures on their own. Neuroregeneration is a viable way to curb neurodegeneration. One of the current approaches is stem cell-based therapy that has been shown to be potentially helpful for the application of neuronal cell replacement for neuroregeneration. It is vital that the neurodegenerative disorder being detected at an early stage as it can provide a chance for treatment that may be helpful to prevent further progression of the fatal disease. Thus, research has focused on developing effective non-invasive diagnostic methods for early detection of these disorders. Molecular diagnostics can provide a powerful method to detect and diagnose various neurological disorders. Such diagnosis can enhance early detection, provide subsequent medical counsel based on medical pathway, as well as to



gain better insight of neurogenesis and hopefully eventual cure of the neurodegenerative diseases. With research reports, reviews, mini-reviews and commentary, this research topic covers a wide range of areas in neurodegeneration research, including diagnosis and prognosis; regulating central nervous system; biomarkers and brain injury induced neurobehavioral outcomes among other timely reports on neurodegeneration.

2.

Record Nr.

UNINA9910788535403321

Autore

Alvarez López Luis

Titolo

The Dominican Republic and the beginning of a revolutionary cycle in the Spanish Caribbean, 1861-1898 [[electronic resource] /] / Luis Alvarez Lopez

Pubbl/distr/stampa

Lanham, MD, : University Press of America, 2009

ISBN

1-283-61572-X

9786613928177

0-7618-4715-4

Descrizione fisica

1 online resource (119 p.)

Disciplina

972.93

Soggetti

Dominican Republic History 1844-1930

Dominican Republic Annexation to Spain

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references (p. [91]-96) and index.

Nota di contenuto

Cover; Title Page; Copyright Page; Dedication Page; Table of Contents; Lists of Graphs and Tables; Foreword; Preface; Acknowledgments; Chapter 1: Seventeen Fundamental Conclusions about the Annexation to Spain and the Restoration War of The Dominican Republic: 1861-1865; Chapter 2: Kidnapping the Rebels' Goods: State and Society Under the Last Spanish Domination of Quisqueya (1863-1865); Chapter 3: Santo Domingo, Puerto Rico and Cuba: Between National Independence and Spanish Colonialism 1844-1859

Chapter 4: Ramon Emeterio Betances and the Revolutionary Cycle in the Spanish Caribbean (From the Restoration War to the Cuban Spanish American Philippines War 1864-1898)Chapter 5: The Spanish Soldiers



in the Last Campaign of Santo Domingo: Diseases, Injuries, Disables and Deaths 1861-1865; Research, Sources and Bibliography; Index

Sommario/riassunto

In this book, Álvarez-López details the history of revolution in the Dominican Republic, an infant independent nation struggling to preserve its political independence from Haiti and from the expansionist policies of northern European countries and the United States.