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Record Nr. |
UNINA9910788378703321 |
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Autore |
Rooke Thom W |
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Titolo |
The quest for cortisone [[electronic resource] /] / Thom Rooke |
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Pubbl/distr/stampa |
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East Lansing [Mich.], : Michigan State University Press, c2012 |
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ISBN |
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1-62895-125-7 |
1-60917-326-0 |
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Descrizione fisica |
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1 online resource (286 p.) |
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Disciplina |
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Soggetti |
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Cortisone - United States - History |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references. |
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Nota di contenuto |
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Contents; Introduction; Chapter 1. Addison and His Disease; Chapter 2. Introducing Dr. Kendall; Chapter 3. Life After the Thyroid; Chapter 4. Introducing Dr. Hench; Chapter 5. Nice Guys, Saints, Eccentrics, and Geniuses; Chapter 6. 1929 and the Decision to Hunt for Cortisone; Chapter 7. Another Kendall False Start, Another Great Announcement; Chapter 8. Kendall Strikes Out Again; Chapter 9. Kendall Presses On; Chapter 10. Score: Szent-Györgyi-1; Kendall-0; Chapter 11. Transitions and Travels; Chapter 12. War Looms; Chapter 13. Hench Meets Kendall |
Chapter 14. World War II and Military Steroid ResearchChapter 15. Plants, Politicians, and More Pessimism; Chapter 16. Good-bye Marker, Hello Sarett; Chapter 17. Hench Returns to Mayo; Chapter 18. Push On? Give Up?; Chapter 19. The Decision to Test Compound E on Rheumatoid Arthritis; Chapter 20. The Amazing Mrs. G.; Chapter 21. A Promising Start; Chapter 22. The Bad and the Ugly; Chapter 23. Progress and Setbacks; Chapter 24. Convincing the Skeptics; Chapter 25. Announcement; Chapter 26. The Prize; Chapter 27. Stockholm; Chapter 28. Aftermath; Chapter 29. Twilight |
Chapter 30. The End of the ShowNotes |
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Sommario/riassunto |
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In 1948, when "Mrs. G.," hospitalized with debilitating rheumatoid arthritis, became the first person to receive a mysterious new compound-cortisone-her physicians were awestruck by her transformation from enervated to energized. After eighteen years of |
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biochemical research, the most intensively hunted biological agent of all time had finally been isolated, identified, synthesized, and put to the test. And it worked. But the discovery of a long-sought "magic bullet" came at an unanticipated cost in the form of strange side effects. This fascinating history recounts the discovery of cortison |
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