| |
|
|
|
|
|
|
|
|
1. |
Record Nr. |
UNINA9910787996403321 |
|
|
Titolo |
Huntington's disease / / edited by Gillian Bates, Sarah Tabrizi and Lesley Jones ; Véronique M. André [and thirty seven others], contributors |
|
|
|
|
|
|
|
Pubbl/distr/stampa |
|
|
New York : , : Oxford University Press, , 2014 |
|
©2014 |
|
|
|
|
|
|
|
|
|
ISBN |
|
0-19-937047-8 |
0-19-937048-6 |
0-19-992915-7 |
|
|
|
|
|
|
|
|
Edizione |
[Fourth edition.] |
|
|
|
|
|
Descrizione fisica |
|
1 online resource (513 p.) |
|
|
|
|
|
|
Collana |
|
Oxford Monographs on Medical Genetics |
|
|
|
|
|
|
Disciplina |
|
|
|
|
|
|
Soggetti |
|
|
|
|
|
|
Lingua di pubblicazione |
|
|
|
|
|
|
Formato |
Materiale a stampa |
|
|
|
|
|
Livello bibliografico |
Monografia |
|
|
|
|
|
Note generali |
|
Description based upon print version of record. |
|
|
|
|
|
|
Nota di bibliografia |
|
Includes bibliographical references at the end of each chapters and index. |
|
|
|
|
|
|
|
|
Nota di contenuto |
|
""Cover""; ""Huntington�s Disease""; ""Series""; ""Copyright""; ""Contents""; ""Contributors""; ""Section one Clinical Aspects of Huntington�s Disease""; ""1 Huntington�s Disease in a Historical Context""; ""2 Clinical Neurology""; ""3 Neuropsychiatry and Neuropsychology""; ""4 Juvenile Huntington�s Disease""; ""5 Premanifest and Early Huntington�s Disease""; ""Section two Genetics of Huntington�s Disease""; ""6 Genetic and Molecular Studies""; ""7 Epidemiology""; ""8 Genetic Counseling and Testing""; ""Section three Neurobiology of Huntington�s Disease"" |
""9 Neuropathology in the Human Brain""""10 Altered Neuronal Circuitry""; ""Section Four Molecular Biology of Huntington�s Disease""; ""11 Normal Function of Huntingtin""; ""12 Structural Biology: Order, Disorder, and Conformational Flux""; ""13 Pathogenic Mechanisms""; ""14 Peripheral Pathology""; ""Section five Therapeutic Interventions in Huntington�s Disease""; ""15 Comprehensive Care""; ""16 Preclinical Experimental Therapeutics""; ""17 Experimental Therapeutics: Moving Forward in Clinical Trials""; ""Index"" |
|
|
|
|
|
|
|
|
Sommario/riassunto |
|
This fourth edition of Huntington's Disease presents a comprehensive summary of the current knowledge of this disease, including the major |
|
|
|
|
|
|
|
|
|
|
|
|
|
scientific and clinical advances that have occurred since publication of the third edition in 2002. Completely updated and expanded, chapters in this volume are organized in five sections: DT Clinical aspects of Huntington's disease, including updated chapters on historical perspectives, neurological, neuropsychiatric, and neuropsychological aspects, and new chapters on juvenile Huntington's and the premanifest and early stages DT The genetics of Huntington |
|
|
|
|
|
|
2. |
Record Nr. |
UNINA9910583583203321 |
|
|
Autore |
Epstein Rachel A. <1970-> |
|
|
Titolo |
In Pursuit of Liberalism : International Institutions in Postcommunist Europe |
|
|
|
|
|
|
|
Pubbl/distr/stampa |
|
|
Johns Hopkins University Press, 2008 |
|
|
|
|
|
|
|
ISBN |
|
|
|
|
|
|
|
|
Descrizione fisica |
|
1 online resource (288 p.) |
|
|
|
|
|
|
Soggetti |
|
|
|
|
|
|
Lingua di pubblicazione |
|
|
|
|
|
|
Formato |
Materiale a stampa |
|
|
|
|
|
Livello bibliografico |
Monografia |
|
|
|
|
|
Sommario/riassunto |
|
Though the fall of the Soviet Union opened the way for states in central and eastern Europe to join the world of market-oriented Western democracies, the expected transitions have not been as easy, common, or smooth as sometimes perceived. Rachel A. Epstein investigates how liberal ideas and practices are embedded in transitioning societies and finds that success or failure depends largely on creating a social context in which incentives held out by international institutions are viewed as symbols of an emerging Western identity in the affected country.Epstein first explains how a liberal worldview and institutions like the European Union, World Bank, the International Monetary Fund, and the North Atlantic Treaty Organization go hand-in-hand and why Western nations assume that a broad and incremental program of incentives to join will encourage formerly authoritarian states to reform |
|
|
|
|
|
|
|
|
|
|
their political and economic systems. Using Hungary, Poland, Romania, and the Ukraine as case studies, she demonstrates the limits of conditionality in the face of national social perceptions and elucidates the three key points around which a consensus within the state must emerge before international institutions can expect liberalization: domestic officials must be uncertain about how changing policies will affect their interests; the status of international and domestic institutions must not be in jeopardy; and the proposed polices must seem credible. In making her case, Epstein cleverly bridges the gap between the rationalist and constructivist schools of thought.Offering new data on and fresh interpretations of reforming central bank policies, privatizing banks with foreign capital, democratizing civil-military relations, and denationalizing defense policy, In Pursuit of Liberalism extends well beyond the scope of previous book-length studies. |
|
|
|
|
|
| |