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1. |
Record Nr. |
UNINA9910787755503321 |
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Titolo |
Stem cell-dependent therapies : mesenchymal stem cells in chronic inflammatory disorders / / edited by Gerhard Gross, Thomas Häupl |
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Pubbl/distr/stampa |
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Berlin : , : Walter de Gruyter GmbH & Company, , [2013] |
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©2013 |
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ISBN |
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Descrizione fisica |
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1 online resource (428 p.) |
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Altri autori (Persone) |
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GrossGerhard <1949-> |
HäuplThomas |
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Disciplina |
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Soggetti |
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Inflammation |
Mesenchymal stem cells - Transplantation |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di contenuto |
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Frontmatter -- Preface -- Contributing authors -- Table of Contents -- 1 Mesenchymal stem cells in the context of stem cell biology / Durand, Charles / Charbord, Pierre -- 2 Are mesenchymal stem cells immune privileged? / Zhang, Shang / Hollander, Anthony P. / Wraith, David C. -- 3 Mesenchymal stem cell therapies for autoimmune diseases / Tyndall, Alan / Bocelli-Tyndall, Chiara -- 4 Mesenchymal stem cells in osteoarthritis and rheumatic disease / Kurtz, Andreas / Oh, Su-Jun -- 5 Mesenchymal stem cells in enthesis formation and repair / Hoffmann, Andrea / Seiffart, Virginia / Laggies, Sandra / Gross, Gerhard -- 6 Mesenchymal stem cells for clinical/therapeutic interventions of graft-versus-host disease / Ringdén, Olle / Sadeghi, Behnam -- 7 Mesenchymal stem cells for graft-versus-host disease in experimental animal models / Sadeghi, Behnam / Ringdén, Olle -- 8 Mesenchymal stem cells and organ transplantation : initial clinical results / Pileggi, Antonello / Xu, Xiumin / Tan, Jianming / Ricordi, Camillo -- 9 Stem cell therapy in patients with ischemic heart disease / Qayyum, Abbas Ali / Kastrup, Jens -- 10 Mesenchymal stem cells as a strategy for the treatment of multiple sclerosis and other diseases of the central nervous system / Cordano, Christian / Kerlero de Rosbo, Nicole / Uccelli, Antonio -- 11 Mesenchymal stem cells for the treatment of inflammatory bowel disease / Dennis, James E. / Lord, James D. -- 12 |
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Mesenchymal stem cells in chronic lung diseases: COPD and lung fibrosis / Weiss, Daniel J. / Rojas, Mauricio -- 13 Mesenchymal stem cells as therapeutics for liver repair and regeneration / Porada, Christopher D. / Almeida-Porada, Graça -- 14 Mesenchymal stem cells attenuate renal fibrosis / Almeida, Danilo Candido de / Taemi Origassa, Clarice Silvia / Bassi, Ênio Jose / Olsen Saraiva Câmara, Niels -- 15 Immunomodulation by mesenchymal stem cells - a potential therapeutic strategy for type 1 diabetes / Mounayar, Marwan / Magee, Ciara N. / Abdi, Reza -- 16 Fibrogenic potential of human multipotent mesenchymal stem cells in inflammatory environments / Gonelle-Gispert, Carmen / Bühler, Léo H. -- 17 Mesenchymal stem cells and the tumor microenvironment / Bergfeld, Scott A. / DeClerck, Yves A. -- 18 Mesenchymal stem cells as a carrier for tumor-targeting therapeutics / Chang, Astra I. / Nolta, Jan A. / Wu, Jian -- 19 Systems biology approach to stem cells, tissues and inflammation / Häupl, Thomas -- Index |
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Sommario/riassunto |
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Multipotent mesenchymal stem cells (MSCs) are a heterogeneous population of cells which reside in a variety of tissues. They differentiate into several mesodermal lineages, secrete a multitude of trophic factors and contribute to tissue homeostasis. MSCs are able to exert immunosuppressive activities by interfering with inflammatory cytokine production and with T- and B-cell proliferation. These immunomodulating properties make MSCs promising candidates for the treatment of chronic inflammatory and autoimmune disorders. There are, however, certain caveats involved including inappropriate migration of cells in the body, immune rejection, tumor formation, or graft versus host disease (GvHD). This book investigates the current state of the MSC-dependent therapy of chronic inflammatory disorders and autoimmune diseases. Among the covered topics are GvHD, chronic kidney, liver and lung disease, ischemic heart and inflammatory bowel disease, diabetes, osteoarthritis, various rheumatic and neurological disorders and, lastly, tumors and solid organ transplantations. This book also questions the immunoprivileged status of MSCs, discusses the therapeutic role of MSCs in experimental animal disease models and their translation to the corresponding human disorders, envisions a role for MSCs in tumor interventions and, lastly, describes a systems biology approach for stem cells and inflammation. |
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2. |
Record Nr. |
UNINA9910790935403321 |
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Autore |
Nur Ofer Nordheimer |
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Titolo |
Eros and tragedy : Jewish male fantasies and the masculine revolution of Zionism / / Ofer Nordheimer Nur ; cover design by Ivan Grave |
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Pubbl/distr/stampa |
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Brighton, Massachusetts : , : Academic Studies Press, , 2014 |
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©2014 |
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ISBN |
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Descrizione fisica |
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1 online resource (224 p.) |
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Collana |
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Israel: Society, Culture, and History |
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Classificazione |
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Disciplina |
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Soggetti |
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Masculinity - Palestine - History |
Jewish men - Palestine - Attitudes - History |
Jewish men - Palestine - Psychology - History |
Zionism |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references. |
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Nota di contenuto |
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Frontmatter -- Table of Contents -- Preface and Acknowledgments -- Introduction -- Chapter I. Eastern Galicia and Vienna: Hashomer, Tse'irei Tsiyon, and the Origins of Hashomer Hatzair -- Chapter II. The "Sexual Problem" in the Youth Movement: From Denial, to Love, to Eros -- Chapter III. Tragic Man: An Aesthetic of Anarchism -- Chapter IV. Eros and Tragedy: Dionysos in the Galilee -- Chapter V. Martin Buber and Gustav Landauer: Gemeinschaft and Subterranean Judaism -- Chapter VI. Dancing, Working, and Public Confessions: The Eda Takes Its Form -- Chapter VII. The Eda of Hashomer Hatzair as Männerbund: A Jewish Male Fantasy Comes Full Central European Circle -- Chapter VIII. The Tragic Hero Metamorphoses into a Sensitive Man -- Bibliography -- Index |
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Sommario/riassunto |
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Between 1920 and 1922, hundreds of members of the Hashomer Hatzair youth movement left the defunct Habsburg Monarchy and sailed to Palestine, where a small group of members of the movement established Upper Bitania, one of the communities that laid the foundation for Israel's kibbutz movement. Their social experiment lasted only eight months, but it gave birth to a powerful myth among |
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Jewish youth which combined a story about a heroic Zionist deed, based on the trope of tragedy, with a model for a new type of community that promised no less than a total, absolute elimination of all physical and mental barriers between isolated individuals and their fusion into one entity. This entity was named "the erotic community." In its quest for human regeneration, Upper Bitania embarked on a journey into a highly specific variant of modern life that, at its core, tried to combine the most profound Nietzscheanism with the insights of Sigmund Freud, all in an anti-capitalist quest for an organic community of "new men." The quest for a "new man" was to compensate for a crisis of manliness and betrays an obsession with masculinity and male bonding, and their effects on the ideal man and woman. |
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