1.

Record Nr.

UNINA9910456514803321

Autore

Wortley Richard (Richard K.)

Titolo

Psychological criminology : an integrative approach / / Richard Wortley

Pubbl/distr/stampa

London ; ; New York : , : Routledge, , 2011

ISBN

1-136-65289-2

1-283-24156-0

9786613241566

0-203-80609-3

Descrizione fisica

1 online resource (286 p.)

Collana

Crime science series ; ; 9

Disciplina

364.019

364.3

Soggetti

Criminal psychology

Criminal anthropology

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Front Cover; Psychological Criminology; Copyright Page; Contents; List ofIllustrations; Acknowledgements; 1.Introduction; What is psychological criminology?; Defining crime and criminals; Debates about the nature of crime and criminality; Psychological theories of crime and criminality: an integrated model; 2.Human nature; The principles of evolution; Evolution and behaviour; Crime-focused evolutionary approaches; Offender-focused evolutionary approaches; Conclusion and evaluation; 3.Heredity; A primer in behavioural genetics; Heritability of criminality

Variations in the heritability of criminalityBeyond behavioural genetics: molecular genetics; Conclusion and evaluation; 4.The brain; Basic brain structures and functions; Psychophysiology and crime; Biochemistry and crime; Neuroanatomy and crime; Neuro-environmental factors and crime; Putting it together: neuropsychological theories of crime; Conclusion and evaluation; 5.Personality; Trait approaches to personality; The single-trait approach and crime; The super-trait approach: Eysenck's three-factor theory of crime; Antisocial personality disorder (APD); Conclusion and evaluation



6.DevelopmentThe biological and environmental foundations of human development; Developmental risk and protective factors for crime; Psychosocial development and crime; Criminal careers; Conclusion and evaluation; 7.Learning; The science of behaviour; Classical conditioning; Operant conditioning; Social learning; Conclusion and evaluation; 8.Cognition; The cognitive revolution; Social cognitive theory; Offender decision-making; Schemas and scripts; Conclusion and evaluation; 9.Situations; What is a situation?; Social psychology; Environmental psychology; Opportunity theories

The person-situation interaction (again)Conclusion and evaluation; 10.Conclusion; The argument in a nutshell; The strengths and limits of integration; Implications for practice; Bibliography; Index

Sommario/riassunto

Psychological Criminology addresses the question: what is it about individuals and their experiences that cause them to commit crime and/or to become criminal?This book provides a comprehensive coverage of psychological theories of crime and criminality, exploring theories focusing on factors present at birth (human nature, heredity); theories that focus on factors that influence the offender over the lifespan (learning, development); and theories focusing on factors present at the crime scene. It emphasizes the connections among the different approaches, and demonstrates how, taken together rather than as rival explanations, they provide a more complete picture of crime and criminality than each provides individually.Theories are arranged throughout the book in a temporal sequence, from distal to proximal causes of crime. The analysis spans 100,000 years, from the evolutionary roots of criminal behaviour in the ancestral environments of early humans on the African savana, to the decision to engage in a specific criminal act.Key features of the book include:a focus on theory – ‘explaining’ crime and criminality,an integrative approach,accessible to readers who do not have a background in psychology.Psychological Criminology highlights the contributions that psychological theory can make to the broader field of criminology; it will be of interest to students, academics, researchers and practitioners in both criminology and forensic psychology.



2.

Record Nr.

UNINA9910787665603321

Titolo

Bacterial toxins : genetics, cellular biology and practical applications / / Edited by Thomas Proft

Pubbl/distr/stampa

Norfolk, England : , : Caister Academic Press, , [2013]

©2013

ISBN

1-908230-70-3

Descrizione fisica

1 online resource (249 p.)

Disciplina

615.95293

Soggetti

Bacterial toxins

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Table of Contents; Chapter 1. Receptor-related Risk Factors for Verotoxin Pathogenesis; Verotoxins and their receptors; Receptor glycolipid; B subunit receptor-binding sites; VT signalling and internalization; Cholesterol masking of VT receptors; New model for VTB subunit pentamer binding plasma membrane Gb3; Cholesterol is key for VT-Gb3 retrograde transport; Regulation of Gb3 biosynthesis; Soluble GSL mimics; Conclusions; References; Chapter 2. The Helicobacter pylori CagA Protein: A Multifunctional BacterialToxin Delivered by Type IV Secretion; Introduction

The cag pathogenicity island and its effector protein CagAThe Cag type IV secretion system as a toxin delivery system; CagA interaction partners and associated effects in host cells; Conclusions; Chapter 3. Pore-forming Toxins; Introduction; Introduction to Staphylococcus aureus α-haemolysin; Nomenclature and early observations; Primary structure and regulation of toxin production; Three-dimensional structure and function; Role in disease pathogenesis; Summary and future perspectives - α-toxin

Introduction to the cholesterol-dependent cytolysins and membrane attack complex/perforin (MACPF) family proteinsGeneral features of the CDC primary structure; The CDC monomer crystal structure; Secretion of the CDCs; Cellular recognition; The CDC membrane anchoring system; The CDC allosteric pathway; Formation of the prepore oligomer; Formation of the pore complex; Ring versus arc oligomers;



The CDCs and bacterial pathogenesis; The membrane attack complex/perforin (MACPF) proteins; Summary and futureperspectives - CDCs andMACPF proteins; References

Chapter 4. Bacterial Enterotoxins as Immunomodulators and Vaccine AdjuvantsIntroduction; Cholera toxin: the prototype for ADP-ribosylating holotoxin adjuvants; LT: a more complex family of holotoxin adjuvants; Are ADP-ribosylating toxins in general good adjuvants?; Taking toxin adjuvant immunomodulation one step further; Concluding remarks; References; Chapter 5. Mobile Genetic Elements as Carriers for Bacterial Virulence Genes; Core and adaptive genome; The mobile bacterial genome; Mobile genetic elements and their role in virulence; Why MGEs encode exotoxins and other virulence factors?

Role of SOS inductionBacteriophage-encoding toxins and other virulence factors; Plasmids encoding toxins; Pathogenicity islands encoding toxins; Open questions; Web resources; References; Chapter 6. The Staphylococcal Superantigen-like Toxins; Introduction; The SSLs - an introduction; Genetics of the ssls; Molecular biology of the SSLs; SSL-related S. aureus immune evasion molecules; Mechanisms of immune evasion mediated by SSLs; Novel SSL-associated applications; Concluding remarks; References; Chapter 7. Botulinum Neurotoxins as Therapeutics; Introduction

Mechanistic basis of BoNTs as therapeutics

Sommario/riassunto

Toxins are virulence determinants that play an important role in microbial pathogenicity and/or evasion of the host immune response. This makes them ideal targets for the development of novel antimicrobial strategies. The potential applications of toxin research extend beyond simply combating microbial pathogens, and include use as novel anti-cancer drugs and other front-line medicines and as tools in neurobiology. In the field of cellular biology, toxins have become invaluable as tools for the manipulation and investigation of fundamental cellular and physiological processes. Research in this