| |
|
|
|
|
|
|
|
|
1. |
Record Nr. |
UNINA9910787640003321 |
|
|
Titolo |
Catecholamine research in the 21st century : abstracts and graphical abstracts, 10th International Catecholamine Symposium, 2012 / / edited by Lee E. Eiden |
|
|
|
|
|
|
|
Pubbl/distr/stampa |
|
|
London : , : Academic Press, , 2013 |
|
|
|
|
|
|
|
ISBN |
|
|
|
|
|
|
Descrizione fisica |
|
1 online resource (xxi, 253 pages) : illustrations (some color) |
|
|
|
|
|
|
Collana |
|
|
|
|
|
|
Disciplina |
|
|
|
|
|
|
Soggetti |
|
|
|
|
|
|
Lingua di pubblicazione |
|
|
|
|
|
|
Formato |
Materiale a stampa |
|
|
|
|
|
Livello bibliografico |
Monografia |
|
|
|
|
|
Note generali |
|
Description based upon print version of record. |
|
|
|
|
|
|
Nota di bibliografia |
|
Includes bibliographical references. |
|
|
|
|
|
|
Nota di contenuto |
|
Front Cover; Catecholamine Research in the 21st Century; Copyright Page; Contents; Preface; THEME A: CATECHOLAMINE BIOSYNTHESIS AND STORAGE; 1. Genetic Manipulation of Catecholamine Signaling in the Mouse; 2. AADC Deficiency: Occurring in Humans; Modeled in Rodents; Treated in Patients; 3. Tyrosine Hydrolylase and Dopamine Beta-Hydroxylase: Role of Common Genetic Variation in Adrenergic Responses to Stress and ...; 4. Pharmacokinetic and Pharmacodynamic Properties of Etamicastat, a New DBH Inhibitor: Comparison to Nepicastat |
5. Estradiol-Mediated Regulation of Gene Expression of Catecholamine Biosynthetic Enzymes: The Role of Membrane-Initiated Sign...6. Structural Basis for Regulation of Tyrosine Hydroxlyase by the Catecholamines; 7. Unique Regulation of TH Gene Expression in Midbrain Dopamine Neurons; 8. Intracellular Stability of Tyrosine Hydroxylase: Phosphorylation and Proteasomal Digestion of the Enzyme; 9. The Peripheral Interaction of Tyrosine Hydroxylase and 14-3-3γ with Negatively Charged Phospholipidic Membranes; References |
10. Dynamic Regulation of Tyrosine Hydroxylase Gene Expression by Key Fate-Determining Transcription Factors during Dopaminergi...11. Analysis of Tyrosine Hydroxylase Isoforms and Phosphorylation in Parkinson's Disease; 12. Non-dopaminergic Neurons Partly Expressing Dopaminergic Phenotype: Functional Significance and Regulation; 13. Developing Brain as an Endocrine Organ: Catecholamines Secretion and |
|
|
|
|
|
|
|
|
|
|
|
Endocrine Action; 14. Brainstem DOPAergic System; 15. Imaging Norepinephrine Transporters in Humans; Translational Research with PET |
16. Imaging the Vesicular Monoamine Transporter (VMAT2) in Neurodegenerative Diseases17. GTP Cyclohydrolase Regulation: Implications for Brain Development and Function; 18. Neonatal Diagnosis of Menkes Disease by a Pattern of Plasma Catechols; 19. Catecholamine Metabolites Affected by the Copper-Dependent Enzyme Dopamine-Beta-Hydroxylase Provide Sensitive Blood and Csf...; 20. Are the Enzymes of the Catecholamine Biosynthetic Pathway Locally Synthesized in the Axon? |
21. Effects of Missense Mutations in Tyrosine Hydroxylase (TH) Found in Patients with Neurological Disorders Attributed to TH D...22. Tetrahydrobiopterin Deficiency Impairs Postnatal Increase of TH Protein via Insufficient Dopamine Biosynthesis; 23. Selective Ablation of Dopamine Beta-Hydroxylase Neurons (Subpopulation of TH Neurons) in the Brain: New Insights into Brain...; 24. Neural Circuit Mechanism for Learning Dependent on Dopamine Transmission: Roles of Striatal Direct and Indirect Pathways in... |
25. Regulation of Tyrosine Hydroxylase by Ser19-Phosphorylation-Dependent Binding to 14-3-3γ |
|
|
|
|
|
|
Sommario/riassunto |
|
Through the use of extended graphical abstracts and some traditional text-only abstracts this collection provides, a record of and roadmap to, the research presented at The Tenth International Catecholamine Symposium (XICS) held in September of 2012. Organized around ten general themes, each is introduced by a short overview identifying interesting research programs, results and potential areas of growth. The collection is a roadmap to key research and future opportunities for new catecholamine research programs and will be of interest to neuroscientists and clinical neurologists interested |
|
|
|
|
|
|
|
| |