1.

Record Nr.

UNINA9910787593503321

Titolo

Monoclonal antibodies in oncology / / editor, Fatih M. Uckun

Pubbl/distr/stampa

London, England : , : Future Medicine Ltd., , [2013]

©2013

ISBN

1-78084-327-5

1-78084-222-8

Edizione

[1st ed.]

Descrizione fisica

1 online resource (85 p.)

Collana

Future Medecine, , 2047-332X

Disciplina

615.37

Soggetti

Monoclonal antibodies - Therapeutic use

Antibody-toxin conjugates - Therapeutic use

Cancer - Immunotherapy

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references at the end of each chapters and index.

Nota di contenuto

Title page; Copyright page; Contents; Foreword. Monoclonal antibodies in contemporary cancer therapy; 1. mAbs targeting CD20 and other lymphocyte CD markers in lymphoma treatment; 2. mAbs targeting CTLA-4 and clinical outcomes; 3. mAbs targeting VEGF/VEGFR and clinical outcomes in cancer treatment; 4. mAbs targeting RANKL in bone metastasis treatment; 5. Novel monoclonal antibody-based therapies for leukemia; Index

Sommario/riassunto

Monoclonal antibodies (mAbs) have been developed to improve the treatment outcome of cancer patients undergoing therapy according to multimodality regimens without a significant increase of treatment-associated toxicity. This five-chapter book provides examples where mAbs that have become part of the standard of care in cancer patients and cancer types that have responded to mAbs