1.

Record Nr.

UNINA9910787331403321

Titolo

Extracellular vesicles in health and disease / / edited by Paul Harrison, Christopher Gardiner, Ian L. Sargent

Pubbl/distr/stampa

Boca Raton, FL : , : CRC Press : , : Pan Stanford Publishing, , [2014]

©2014

ISBN

0-429-06801-8

981-4411-98-1

Descrizione fisica

1 online resource (474 p.)

Disciplina

574.874

Soggetti

Coated vesicles

Cell interaction - Research

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references.

Nota di contenuto

Front Cover; Contents; Preface; Chapter 1 Overview of Extracellular Vesicles in Health and Disease; Chapter 2 The Biogenesis of Exosomes; Chapter 3 Extracellular Vesicle- Mediated Epigenetic Reprogramming of Cells; Chapter 4 An Overview of Novel and Conventional Methods to Detect Extracellular Vesicles; Chapter 5 Preanalytical Variables; Chapter 6 Procoagulant Assays; Chapter 7 Capture- Based Assays for Extracellular Vesicles within the Blood; Chapter 8 Flow Cytometry; Chapter 9 Atomic Force Microscopy Measurement of Extracellular Vesicles Derived from Plasma

Chapter 10 Light- Scattering Methods to Characterize Extracellular VesiclesChapter 11 Nanoparticle Tracking Analysis; Chapter 12 Extracellular Vesicle Proteomic Analysis; Chapter 13 Microvesicles and Exosomes in Cancer; Chapter 14 Extracellular Vesicles and Tissue Factor; Chapter 15 Extracellular Vesicles in Normal Pregnancy and Pre- Eclampsia; Chapter 16 Extracellular Vesicles in Cardiovascular Disease; Chapter 17 Extracellular Vesicles in Immunology; Back Cover

Sommario/riassunto

Interest in the role of extracellular vesicles (microvesicles and exosomes) is expanding rapidly. It is now apparent that far from being merely cellular debris, these vesicles play a key role in cell-to-cell communication and signaling. Moreover, they are significantly elevated



in a number of diseases. This raises the question of their direct role in pathogenesis as well as their possible use as biomarkers. This book stems from the first international meeting on ""Microvesicles and Nanovesicles in Health and Disease"" held at Magdalen College, Oxford, in 2010. The purpose of t