1.

Record Nr.

UNINA9910786834803321

Titolo

Comparative immunoglobulin genetics / / edited by Azad K. Kaushik, DVM, DSc (Paris), and Yfke Pasman, PharmD, MSc, University of Guelph, Guelph, Ontario Canada

Pubbl/distr/stampa

Waretown, N.J. : , : Apple Academic Press, Inc., , [2014]

©2014

ISBN

1-77463-334-5

0-429-15995-1

1-4822-4355-5

Edizione

[First edition.]

Descrizione fisica

1 online resource (258 p.)

Disciplina

616.07/98

Soggetti

Immunoglobulins - Genetics

Immunoglobulin genes

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references.

Nota di contenuto

Front Cover; About The Editors; Contents; List Of Contributors; List Of Abbreviations; Preface; Chapter 1 Variable Lymphocyte Receptor-based Adaptive Immunity In The Agnathan Sea Lamprey; Chapter 2 Agnathan Sea Lamprey Tetrapods; Chapter 3 The Immunoglobulin Genes Of Bats; Chapter 4 Marsupial And Monotreme Immunoglobulin Genetics; Chapter 5 Organization Of The Immunoglobulin Heavy- And Light-chain Loci In The Rat; Chapter 6 Generation Of The Antibody Repertoire In Rabbits: Role Of Gut-associated Lymphoid Tissues; Chapter 7 The Immunoglobulin Genes Of Domestic Swine

Chapter 8 Bovine Immunoglobulin Genetics: Novel Phylogenetic PerspectiveChapter 9 Informatic Tools For Immunoglobulin Gene Sequence Analysis; Back Cover

Sommario/riassunto

This contemporary book covers significant new knowledge that has emerged during the last two decades and, thus, provides novel antibody phylogenetic perspectives relevant to development of new antibody-based therapeutics and vaccines. It fills a much-needed niche in the area of immunoglobulin genetics across species from a comparative perspective. New insights and perspectives from



immunoglobulin genetics from species such as sea lamprey, cattle, marsupial, bat, rat, rabbit, and swine-other species than the traditional subjects of mice and humans-are relevant to antibody design and engineer