The intelligent international negotiator / / Eliane Karsaklian

• Record Nr.: UNINA9910786411603321
• Autore: Karsaklian Eliane
• Pubbl/distr/stampa: New York, New York (222 East 46th Street, New York, NY 10017) : , : Business Expert Press, , 2014
• ISBN: 1-60649-807-X
• Edizione: [First edition.]
• Descrizione fisica: 1 online resource (174 p.)
• Collana: International business collection, , 1948-2760
• Disciplina: 302.3
• Soggetti: Negotiation; Negotiation in business
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Part of: 2014 digital library.
• Nota di bibliografia: Includes bibliographical references (pages 151-152) and index.
• Nota di contenuto: 1. What international negotiation is not -- 2. Merging culture with negotiation -- 3. International negotiating styles -- 4. The international negotiators' toolkit -- Conclusion -- References -- Index.
• Sommario/riassunto: When reading this book you will be familiar with strategies, stories, facts, and tools that intelligent international negotiators use in order to succeed in their negotiations worldwide. The unique integrative cross-cultural approach to negotiating provided by this book will help you to have a different and innovative perception of what negotiating means today. Businesspeople negotiate every day, everywhere around the world. Some are more culturally aware and some are much less. Some forget that negotiation is, first of all, a human interaction. Some still think that negotiation rhymes with competition. But after reading this book, you will approach negotiation from another perspective. More human, more pleasant, and more effective. The Intelligent International Negotiator is a ready-to-use book that you will read and digest very quickly, with inputs you will use immediately.

Modern alkaloids : structure, isolation, synthesis and biology / / edited by Ernesto Fattorusso and Orazio Taglialatela-Scafati

• Record Nr.: UNINA9911019549103321
• Pubbl/distr/stampa: Weinheim, : Wiley-VCH, c2008
• ISBN: 9786611311810; 9781281311818; 1281311812; 9783527621071; 3527621075; 9783527621088; 3527621083
• Descrizione fisica: 1 online resource (691 p.)
• Altri autori (Persone): FattorussoErnesto; Taglialatela-ScafatiOrazio
• Disciplina: 572.549
• Soggetti: Alkaloids - Structure; Alkaloids
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Modern Alkaloids; Contents; Preface; List of Contributors; I Bioactive Alkaloids: Structure and Biology; 1 Ecological Roles of Alkaloids; 1.1 Introduction: Defense Strategies in Plants; 1.2 Ecological Roles of Alkaloids; 1.3 Modes of Action; 1.3.1 Unspecific Interactions; 1.3.2 Specific Interactions; 1.3.3 Cytotoxicity of Alkaloids; 1.4 Evolution of Alkaloidal Defense Systems; 1.5 Conclusions; 2 Antitumor Alkaloids in Clinical Use or in Clinical Trials; 2.1 Introduction; 2.2 Antitumor Alkaloids in Clinical Use; 2.2.1 Vinca Alkaloids; 2.2.1.1 Vinblastine (VLB, 1); 2.2.1.2 Vincristine (VCR, 2); 2.2.1.3 Vindesine (VDS, 3)2.2.1.4 Vinorelbine (VRLB, 4); 2.2.1.5 Vinflunine (VFL, 5); 2.2.2 Camptothecin and Analogs; 2.2.2.1 Camptothecin (CPT, 6); 2.2.2.2 Irinotecan (CPT-11); 2.2.2.3 Topotecan; 2.2.2.4 Exatecan; 2.2.2.5 Gimatecan; 2.2.2.6 Karenitecin; 2.2.2.7 Lurtotecan; 2.2.2.8 Rubitecan (9-nitrocamptothecin); 2.2.3 Taxanes; 2.2.3.1 Paclitaxel; 2.2.3.2 Docetaxel; 2.3 Antitumor Alkaloids in Clinical ; Trials; 2.3.1 Ecteinascidin-743 (Yondelis, Trabectedin); 2.3.2 7-Hydroxystaurosporine (UCN-01); 2.3.3 Ellipticine and Analogs; 2.3.4 Acronycine and Analogs; 2.3.5 Colchicine and Analogs; 2.3.6 Ukrain2.4 Alkaloids Used for MDR Reversal; 2.4.1 Cinchona Alkaloids; 2.4.2 Dofequidar Fumarate (MS-209); 2.5 Alkaloids Used for Cancer Prevention; 2.6 Conclusions; 2.7 Acknowledgments; 3 Alkaloids and the Bitter Taste; 3.1 Introduction; 3.2 The Bitter Taste Chemoreception Mechanism; 3.3 Bitter Alkaloids in Food; 3.4 The Bitter Taste of Alkaloids in Other Drugs and Poisons; 3.5 Alkaloids and Taste in Insects; 3.6 The Bitter Taste of Alkaloids: Should We Avoid, Mask, or Understand?; 3.7 Acknowledgments; 4 Capsaicin and Capsaicinoids; 4.1 Introduction; 4.2 What Is an Alkaloid? Is Capsaicin an Alkaloid?4.3 Diversity, Biosynthesis, and Metabolism of Capsaicinoids; 4.4 Quantization of Capsaicinoids and Their Distribution in Chili Pepper; 4.5 Isolation and Synthesis of Capsaicin; 4.6 TRV1 as the Biological Target of Capsaicin and the Ecological Raison d'être of Capsaicinoids: A Molecular View; 4.7 Naturally Occurring Analogs and Antagonists of Capsaicin and Endogenous Vanilloids; 4.8 Structure-Activity Relationships of Capsaicinoids; 4.9 Molecular Gastronomy of Hot Food; 4.9.1 Biomedical Relevance of Capsaicin-Induced Trigeminal Responses; 4.9.2 Effect of Capsaicin on Taste4.9.3 Gustatory Sweating; 4.9.4 Gustatory Rhinitis; 4.9.5 Hot Food Mitridatism; 4.9.6 Effect of Capsaicin on Digestion; 4.9.7 Capsaicin and Stomach Cancer; 4.9.8 The Effect of Age and Sex on the Sensitivity to Capsaicin; 4.9.9 Capsaicin as a Slimming Agent; 4.9.10 Quenching Capsaicin; 4.9.11 Chilies and Olive Oil; 4.9.12 Who Should Avoid Chilies?; 4.9.13 How can the Pungency of Chilies be Moderated?; 4.9.14 Psychology of Pepper Consumption; 4.10 Conclusions; 4.11 Acknowledgments; 5 Glycosidase-Inhibiting Alkaloids: Isolation, Structure, and Application; 5.1 Introduction
• Sommario/riassunto: This book presents all important aspects of modern alkaloid chemistry, making it the only work of its kind to offer up-to-date and comprehensive coverage. While the first part concentrates on the structure and biology of bioactive alkaloids, the second one analyzes new trends in alkaloid isolation and structure elucidation, as well as in alkaloid synthesis and biosynthesis.A must for biochemists, organic, natural products, and medicinal chemists, as well as pharmacologists, pharmaceutists, and those working in the pharmaceutical industry.