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1. |
Record Nr. |
UNINA9910786204703321 |
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Autore |
Hamilton Alexander <1757-1804.> |
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Titolo |
The revolutionary writings of Alexander Hamilton [[electronic resource] /] / edited and with an introduction by Richard B. Vernier ; with a foreword by Joyce O. Appleby |
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Pubbl/distr/stampa |
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Indianapolis, Ind., : Liberty Fund, c2008 |
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ISBN |
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Descrizione fisica |
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1 online resource (233 p.) |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Political science - United States - History - 18th century |
United States Politics and government 1775-1783 |
United States Politics and government 1783-1809 |
United States History Revolution, 1775-1783 |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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""Alexander Hamilton, The Revolutionary Writings Of ""; ""Front Matter ""; ""Title Page ""; ""Publishing Details ""; ""Table of Contents, p. v ""; ""Foreword by Joyce O. Appleby, p. vii ""; ""Introduction by Richard B. Vernier, p. xi ""; ""Hamilton Chronolgy, p. xxiii ""; ""A Full Vindication, p. 1 ""; ""The Farmer Refuted, p. 41 ""; ""Remarks on the Quebec Bill, p. 137 ""; ""No. I, p. 141 ""; ""No. II, p. 145 ""; ""Publius, p. 153 ""; ""Letter I, p. 157 ""; ""Letter II, p. 159 ""; ""Letter III, p. 162 ""; ""The Continentalist, p. 165 ""; ""No. 1, p. 169 ""; ""No. II , p. 172 "" |
""No. III, p. 176 """"No. IV, p. 182 ""; ""No. V, p. 187 ""; ""No. VI, p. 194 ""; ""Index, p. 201 "" |
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2. |
Record Nr. |
UNINA9910437796703321 |
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Titolo |
Identification of ligand binding site and protein-protein interaction area / / Irena Roterman-Konieczna, editor |
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Pubbl/distr/stampa |
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Dordrecht, : Springer, 2013 |
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ISBN |
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Edizione |
[1st ed. 2013.] |
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Descrizione fisica |
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1 online resource (172 p.) |
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Collana |
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Focus on structural biology, , 1571-4853 ; ; v. 8 |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Ligand binding (Biochemistry) |
Protein binding |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Contributors -- Foreword -- Chapter 1 SuMo, J-A. Chemelle, E. Bettler, CH. Combet, R. Terreux, CH. Geourjon, G. Deleage -- Chapter 2 Identification of pockets on protein surface to predict protein–ligand binding sites, Binding Huang -- Chapter 3 Can the structure of the hydrophobic core determine the complexation site?, M. Banach, L. Konieczny, I. Roterman -- Chapter 4 Comparative analysis of techniques oriented on the recognition of ligand binding area in proteins, P. Alejster, M. Banach, W. Jurkowski, D. Marchewka, I. Roterman -- Chapter 5 Docking predictions of protein-protein interactions and their assessment, Joel Janin -- Chapter 6 Prediction of protein-protein binding interfaces, D. Marchewka, W. Jurkowski, M. Banach, I. Roterman -- Chapter 7 Support for Cooperative Experiments in e-Science: From Scientific Workflows to Knowledge Sharing, A. Belloum, R. Cushing, S. Koulouzis, V. Korkhov, D. Vasunin, V. Guevara-Masis, Z. Zhao, M. Bubak -- Index. |
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Sommario/riassunto |
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This volume presents a review of the latest numerical techniques used to identify ligand binding and protein complexation sites. It should be noted that there are many other theoretical studies devoted to predicting the activity of specific proteins and that useful protein data can be found in numerous databases. The aim of advanced computational techniques is to identify the active sites in specific proteins and moreover to suggest a generalized mechanism by which such protein-ligand (or protein-protein) interactions can be effected. |
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Developing such tools is not an easy task – it requires extensive expertise in the area of molecular biology as well as a firm grasp of numerical modeling methods. Thus, it is often viewed as a prime candidate for interdisciplinary research. |
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