Networks, models and applications [[electronic resource] /] / edited by Isidore Rigoutsos & Gregory Stephanopoulos

• Record Nr.: UNINA9910784862303321
• Pubbl/distr/stampa: Oxford ; ; New York, : Oxford University Press, c2007
• ISBN: 0-19-770210-4; 1-280-84622-4; 0-19-534578-9; 1-4294-5929-8
• Descrizione fisica: 1 online resource (360 p.)
• Collana: Series in systems biology; Systems biology ; ; 2
• Altri autori (Persone): RigoutsosIsidore; StephanopoulosG
• Disciplina: 570
• Soggetti: Computational biology; Genomics; Bioinformatics
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Contents; Contributors; Systems Biology: A Perspective; 1 Mass Spectrometry in Systems Biology; 2 Mathematical Modeling and Optimization Methods for De Novo Protein Design; 3 Molecular Simulation and Systems Biology; 4 Global Gene Expression Assays: Quantitative Noise Analysis; 5 Mapping the Genotype-Phenotype Relationship in Cellular Signaling Networks: Building Bridges Over the Unknown; 6 Integrating Innate Immunity into a Global "Systems" Context: The Complement Paradigm Shift; 7 Systems Biotechnology: Combined in Silico and Omics Analyses for the Improvement of Microorganisms for Industrial Applications 8 Genome-Scale Models of Metabolic and Regulatory Networks; 9 Biophysical Models of the Cardiovascular System; 10 Embryonic Stem Cells as a Module for Systems Biology; Index
• Sommario/riassunto: 1. Mass Spectrometry in Systems Biology 3, Cristian I. Ruse & John R. Yates III. 2. Mathematical Modeling and Optimization Methods for De Novo Protein Design 42, C. A. Floudas & H. K. Fung. 3. Molecular ; Simulation and Systems Biology 67, William C. Swope, Jed W. Pitera, & Robert S. Germain. 4. Global Gene Expression Assays: Quantitative Noise Analysis 103, G. A. Held, Gustavo Stolovitzky, & Yuhai Tu. 5. Mapping the Genotype-Phenotype Relationship in Cellular Signaling Networks: Building Bridges Over the Unknown 137, Jason A. Papin, Erwin P. Gianchandani, & Shankar Subramaniam. 6. Integrating I