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Record Nr. |
UNINA9910784784103321 |
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Autore |
Knowles Margaret A |
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Titolo |
Introduction to the cellular and molecular biology of cancer [[electronic resource] /] / Margaret A. Knowles, Peter J. Selby |
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Pubbl/distr/stampa |
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New York, : Oxford University Press, 2005 |
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ISBN |
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1-383-02984-9 |
1-280-75813-9 |
0-19-151381-4 |
1-4294-2155-X |
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Edizione |
[4th ed.] |
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Descrizione fisica |
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1 online resource (555 p.) |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Cancer - Molecular aspects |
Cancer cells |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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"Oxford bioscience"--Cover. |
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Nota di contenuto |
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Contents; Contributors; 1 What is cancer?; 2 The causes of cancer; 3 Inherited susceptibility to cancer; 4 DNA repair and cancer; 5 Epigenetic events in cancer; 6 Molecular cytogenetics of cancer; 7 Oncogenes; 8 Tumour suppressor genes; 9 The cancer cell cycle; 10 Cellular immortalization and telomerase activation in cancer; 11 Growth factors and their signalling pathways in cancer; 12 Apoptosis: molecular physiology and significance for cancer therapeutics; 13 Mechanisms of viral carcinogenesis; 14 Cytokines and cancer; 15 Hormones and cancer; 16 The spread of tumours; 17 Tumour angiogenesis |
18 Stem cells, haemopoiesis, and leukaemia19 Animal models of cancer; 20 The immunology of cancer; 21 The molecular pathology of cancer; 22 From transcriptome to proteome; 23 Local treatment of cancer; 24 Chemotherapy; 25 Radiotherapy and molecular radiotherapy; 26 Monoclonal antibodies and therapy; 27 Immunotherapy of cancer; 28 Cancer gene therapy; 29 Screening; 30 Conclusions and prospects; Index |
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Sommario/riassunto |
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. What is cancer?, L.M. Franks and Margaret A. Knowles. 2. The causes of cancer, Naomi Allen, Robert Newton, Amy Berrington de Gonzalez, Jane Green, Emily Banks, and Timothy J. Key. 3. Inherited Susceptibility |
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to Cancer, D. Timothy Bishop. 4. DNA Repair and Cancer, Beate Koberle, John P. Wittschieben, and Richard D. Wood. 5. Epigenetic Events in Cancer, Jonathan C. Cheng and Peter A. Jones. 6. Molecular Cytogenetics of Cancer, Denise. Sheer and Janet Shipley. 7. Oncogenes, Margaret A. Knowles. 8. Tumour suppressor genes, Sonia Lain and David P. Lane. 9. The cancer cell cycle, Chris J. Norbury. |
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