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1. |
Record Nr. |
UNINA9910144704303321 |
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Titolo |
Airway smooth muscle in asthma and COPD [[electronic resource] ] : biology and pharmacology / / edited by Kian Fan Chung |
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Pubbl/distr/stampa |
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Hoboken, N.J. ; ; Chichester, : Wiley, 2008 |
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ISBN |
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1-282-34322-X |
9786612343223 |
0-470-75422-2 |
0-470-75421-4 |
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Descrizione fisica |
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1 online resource (332 p.) |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Respiratory muscles - Physiology |
Smooth muscle - Physiology |
Respiratory muscles - Molecular aspects |
Smooth muscle - Molecular aspects |
Respiratory agents |
Respiratory organs - Diseases - Treatment |
Respiratory therapy |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Airway Smooth Muscle; Contents; List of Contributors; 1 Biophysical basis of airway smooth muscle contraction and hyperresponsiveness in asthma; 1.1 Introduction; 1.2 Airway hyperresponsiveness; 1.3 Classical behaviour of airway smooth muscle and the balance of static forces; 1.4 Shortening velocity and other manifestations of muscle dynamics; 1.5 Biophysical characterization of airway smooth muscle: bronchospasm in culture?; 1.6 Mechanical plasticity: a nonclassical feature of airway smooth muscle; 1.7 Recent observations; 1.8 Future directions; References |
2 Dynamics of cytoskeletal and contractile protein organization: an emerging paradigm for airway smooth muscle contraction2.1 Introduction; 2.2 Molecular structure and organization of contractile and cytoskeletal filaments in the airway smooth muscle cell; 2.3 Cytoskeletal dynamics and airway smooth muscle contraction; |
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References; 3 Airway smooth muscle: role in airway constrictor hyperresponsiveness; 3.1 What is airway constrictor hyperresponsiveness (AHR)?; 3.2 Is AHR ever good?; 3.3 Potential mechanisms leading to airflow obstruction |
3.4 Potential abnormalities of airway smooth muscle (ASM)3.5 If ASM is dysfunctional, how did it get that way?; 3.6 Summary; Acknowledgements; References; 4 Airway smooth muscle phenotypic and functional plasticity; 4.1 Introduction; 4.2 Historical perspective: smooth muscle phenotype plasticity; 4.3 Features of phenotype plasticity; 4.4 Mechanisms for phenotypic plasticity; 4.5 Functional plasticity of airway smooth muscle: role in asthma pathogenesis; 4.6 Concluding remarks; References; 5 Airway smooth muscle proliferation: insights into mechanisms regulating airway smooth muscle mass |
5.1 Increases in airway smooth muscle (ASM) mass and the functional consequences5.2 Growth factors, inflammatory mediators and cytokines modulate ASM proliferation; References; 6 Airway smooth muscle bidirectional interactions with extracellular matrix; 6.1 Overview; 6.2 Introduction; 6.3 Airway extracellular matrix (ECM) in health and disease; 6.4 Integrins; 6.5 Airway smooth muscle (ASM) as a modulator of airway ECM; 6.6 Airway ECM as modulator of ASM function; 6.7 Impact of anti-asthma therapy on ASM-ECM interactions; 6.8 Conclusions; Acknowledgements; References |
7 Airway smooth muscle interaction with mast cells7.1 Introduction; 7.2 Mast cell mediators alter smooth muscle function; 7.3 Smooth muscle cells induce mast cell chemotaxis; 7.4 Mast cells can adhere to airway smooth muscle; 7.5 Conclusion; Acknowledgements; References; 8 Airway smooth muscle synthesis of inflammatory mediators; 8.1 Introduction; 8.2 Lipid mediators; 8.3 Chemokines; 8.4 Growth and remodelling factors; 8.5 Conclusions; References; 9 Airway smooth muscle in experimental models; 9.1 Introduction; 9.2 Methods of assessment of airway smooth muscle (ASM) function |
9.3 Potential mechanisms by which ASM properties may contribute to airway responsiveness |
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Sommario/riassunto |
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In this book, leading researchers in medicine and molecular pharmacology explain the cellular mechanisms that control airway smooth muscle. The means by which these are disrupted in disease, and the pharmacologic strategies by which they may be modified are discussed and future therapeutic interventions are identified. Aimed at specialists in pulmonology, this volume provides the clinician with the most up to date information on one of the core physiological processes in airway disease, and offers insights into current and future approaches to management. Authori |
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2. |
Record Nr. |
UNINA9910784771903321 |
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Autore |
Peskin Victor <1967-> |
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Titolo |
International justice in Rwanda and the Balkans : virtual trials and the struggle for state cooperation / / Victor Peskin [[electronic resource]] |
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Pubbl/distr/stampa |
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Cambridge : , : Cambridge University Press, , 2008 |
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ISBN |
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1-107-18064-3 |
1-281-24345-0 |
9786611243456 |
0-511-79058-9 |
0-511-37802-5 |
0-511-37714-2 |
0-511-37620-0 |
0-511-37467-4 |
0-511-37891-2 |
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Descrizione fisica |
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1 online resource (xxi, 272 pages) : digital, PDF file(s) |
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Disciplina |
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Soggetti |
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Criminal justice, Administration of - International cooperation |
International criminal courts |
Serbia Politics and government |
Croatia Politics and government |
Rwanda History Civil War, 1994 Atrocities |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Title from publisher's bibliographic system (viewed on 05 Oct 2015). |
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Nota di bibliografia |
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Includes bibliographical references (p. 259-262) and index. |
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Nota di contenuto |
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International war crimes tribunals and the politics of state cooperation -- Slobodan Milošević and the politics of state cooperation -- International justice and Serbia's troubled democratic transition -- Franjo Tuđman and the politics of international justice -- The politics of state cooperation in Croatia's democratic era -- Rwanda virtual trials, international justice, and the politics of shame -- The struggle to create the international criminal tribunal for Rwanda -- "Trials of cooperation" and the battles for Karamira and Barayagwiza -- Investigating Rwandan patriotic front atrocities and the politics of bearing witness -- Victor's justice revisited : the prosecutor vs. Kagame |
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-- Thepresent and future of international criminal justice. |
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Sommario/riassunto |
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Today's international war crimes tribunals lack police powers, and therefore must prod and persuade defiant states to co-operate in the arrest and prosecution of their own political and military leaders. Victor Peskin's comparative study traces the development of the capacity to build the political authority necessary to exact compliance from states implicated in war crimes and genocide in the cases of the International War Crimes Tribunals for the former Yugoslavia and Rwanda. Drawing on 300 in-depth interviews with tribunal officials, Balkan and Rwandan politicians, and Western diplomats, Peskin uncovers the politicized, protracted, and largely behind-the-scenes tribunal-state struggle over co-operation. |
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3. |
Record Nr. |
UNINA9910703398603321 |
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Titolo |
The commercial storage of fruits, vegetables, and florist and nursery stocks |
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Pubbl/distr/stampa |
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[Washington, D.C.], : U.S. Dept. of Agriculture, Agricultural Research Service, 1986 |
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Descrizione fisica |
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Soggetti |
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Cold storage |
Cut flowers |
Fruit |
Nursery stock |
Storage |
Vegetables |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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