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Record Nr. |
UNINA9910784647503321 |
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Autore |
Chandrasoma Para |
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Titolo |
GERD [[electronic resource] ] : reflux to esophageal adenocarcinoma / / Parakrama T. Chandrasoma, Tom DeMeester |
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Pubbl/distr/stampa |
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ISBN |
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1-4933-0073-3 |
1-280-63664-5 |
9786610636648 |
0-08-046474-2 |
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Descrizione fisica |
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1 online resource (482 p.) |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Gastroesophageal reflux |
Esophagus - Cancer |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Front cover; Title page; Copyright page; Table of contents; Preface; CHAPTER 1: Overview of Gastroesophageal Reflux Disease; PHYSIOLOGICAL VERSUS PATHOLOGICAL REFLUX; PREVALENCE OF GASTROESOPHAGEAL REFLUX DISEASE; HISTOLOGIC DEFINITION OF GASTROESOPHAGEAL REFLUX DISEASE; PREVALENCE OF BARRETT ESOPHAGUS; MANAGEMENT OF BARRETT ESOPHAGUS; PREVALENCE OF REFLUX-INDUCED ADENOCARCINOMA; CHAPTER 2: The Past, Present, and Future of Columnar-Lined (Barrett) Esophagus; THE HISTORY OF COLUMNAR-LINED ESOPHAGUS; THE REASONS FOR CONFUSION; HISTORICAL EVOLUTION OF COLUMNAR-LINED (BARRETT) ESOPHAGUS |
THE STATE OF THE ART AND TODAY'S PROBLEMSSOLUTIONS TO THE PROBLEM AND WHAT WE HOPE TO SHOW; CHAPTER 3: Fetal Development of the Esophagus and Stomach; THE STUDY OF EMBRYOLOGY OF THE FOREGUT; EARLY DEVELOPMENT OF THE GASTROINTESTINAL TRACT; EARLY DEVELOPMENT OF THE FOREGUT; EPITHELIAL DEVELOPMENT IN THE FETAL ESOPHAGUS; EPITHELIAL DEVELOPMENT IN THE FETAL STOMACH; EPITHELIAL DEVELOPMENT IN THE FETAL GASTROESOPHAGEAL JUNCTION; SUMMARY OF EPITHELIAL DEVELOPMENT OF THE ESOPHAGUS; CONTROL OF FOREGUT EPITHELIAL |
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DEVELOPMENT; CHAPTER 4: Normal Anatomy |
Present Definition of the Gastroesophageal JunctionANATOMY AND PHYSIOLOGY; ENDOSCOPIC/GROSS LANDMARKS; THE MEANING OF ENDOSCOPIC/GROSS LANDMARKS; PRESENT DEFINITION OF THE GASTROESOPHAGEAL JUNCTION; WHAT IS THE CARDIA? LET'S REMOVE THIS TERM FROM OUR VOCABULARY; THE LOGICAL CONCLUSION THAT SHOULD BE TESTED; CHAPTER 5: Histologic Definitions and Diagnosis of Epithelial Types; DEFINITIONS; PROBLEMS WITH THE DEFINITIONS; DIAGNOSIS OF DIFFERENT EPITHELIAL TYPES; CHAPTER 6: Cardiac Mucosa; WHAT IS CARDIAC MUCOSA?; WHERE IS CARDIAC MUCOSA LOCATED?; IS CARDIAC MUCOSA PRESENT IN EVERYONE? |
WHAT IS OXYNTOCARDIAC MUCOSA, AND WHERE IS IT?HOW MUCH CARDIAC AND OXYNTOCARDIAC MUCOSA ARE PRESENT?; WHAT DOES THE PRESENCE/ABSENCE AND AMOUNT OF CARDIAC MUCOSA MEAN?; WHAT DOES INCREASING LENGTH OF CARDIAC MUCOSA MEAN?; A HUMAN EXPERIMENT; SUMMARY STATEMENT REGARDING CARDIAC MUCOSA; CHAPTER 7: New Histologic Definitions of Esophagus, Stomach, and Gastroesophageal Junction; LET US ESTABLISH COMMON GROUND IN HISTOLOGY; LET US UNDERSTAND THE PROBLEM; NORMAL HISTOLOGY OF THE ESOPHAGUS AND STOMACH: A STATEMENT OF FACT AND NEW HISTOLOGIC DEFINITIONS; APPLICATION OF THESE DEFINITIONS TO PRACTICE |
CHAPTER 8: Pathology of Reflux Disease at a Cellular Level: Part 1-Damage to Squamous Epithelium and Transformation into Cardiac MucosaREFLUX-INDUCED DAMAGE OF THE SQUAMOUS EPITHELIUM; COLUMNAR METAPLASIA OF THE SQUAMOUS EPITHELIUM; SUMMARY; CHAPTER 9: The Pathology of Reflux Disease at a Cellular Level: Part 2-Evolution of Cardiac Mucosa to Oxyntocardiac Mucosa and Intestinal Metaplasia; HISTOLOGIC COMPOSITION OF COLUMNAR-LINED ESOPHAGUS; CARDIAC TO OXYNTOCARDIAC MUCOSA: THE BENIGN GENETIC SWITCH; CARDIAC MUCOSA TO INTESTINAL METAPLASIA: THE SECOND GENETIC SWITCH |
CHAPTER 10: Pathology of Reflux Disease at a Cellular Level: Part 3-Intestinal (Barrett) Metaplasia to Carcinoma |
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Sommario/riassunto |
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The increasing incidence of esophageal adenocarcinoma has created an enormous interest and stimulus for research in this area. GERD brings together, for the first time, a vast amount of disparate literature and documents the entire pathogenesis of reflux disease in one place. The book presents reflux carditis as a new diagnostic criterion of GERD and for the first time defines the dilated end-stage esophagus and the earliest microscopic phase of GERD that is missed by present diagnostic criteria. GERD presents both clinical and pathological information and is meant to be used as |
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