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Record Nr. |
UNINA9910784562303321 |
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Autore |
Sanes Dan Harvey |
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Titolo |
Development of the nervous system [[electronic resource] /] / Dan H. Sanes, Thomas A. Reh, William A. Harris |
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Pubbl/distr/stampa |
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Amsterdam ; ; Boston, : Elsevier, 2006 |
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ISBN |
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1-280-96696-3 |
9786610966967 |
0-08-047249-4 |
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Edizione |
[2nd ed.] |
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Descrizione fisica |
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1 online resource (388 p.) |
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Altri autori (Persone) |
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RehThomas A |
HarrisWilliam A |
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Disciplina |
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Soggetti |
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Developmental neurophysiology |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references (p. 323-360). |
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Nota di contenuto |
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Cover; Contents; Preface to the First Edition; Preface to the Second Edition; Chapter 1: Neural Induction; Development and Evolution of Neurons; Early Embryology of Metazoans; Derivation of Neural Tissue; Interactions with Neighboring Tissues in Making Neural Tissue; The Molecular Nature of the Neural Inducer; Conservation of Neural Induction; Interactions Among the Ectodermal Cells in Controlling Neuroblast Segregation; Notch, Delta, and Achaete Scute Genes in Vertebrates; Linking Induction to Proneural Activity; Summary; Chapter 2: Polarity and Segmentation |
Regional Identity of the Nervous SystemThe Anterior-Posterior Axis and HOX Genes; HOX Gene Function in the Nervous System; Signaling Molecules that Pattern the Anterior-Posterior Axis in Vertebrates: Heads or Tails; Organizing Centers in the Developing Brain; Forebrain Development, Prosomeres, and PAX Genes; Dorsal-Ventral Polarity in the Neural Tube; Dorsal Neural Tube and Neural Crest; Patterning the Cerebral Cortex; Summary; Chapter 3: Genesis and Migration; Cell-Cycle Genes Control the Number of Neurons Generated during Development |
Cell Interactions Control the Number of Cells Made by ProgenitorsThe Generation of Neurons and GLIA; Cerebral Cortex Histogenesis; The Subventricular Zone: A Secondary Zone of Neurogenesis; Cerebellar |
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Cortex Histogenesis; Molecular Mechanisms of Neuronal Migration; Postembryonic and Adult Neurogenesis; Summary; Chapter 4: Determination and Differentiation; Transcriptional Hierarchies in Invariant Lineages; Spatial and Temporal Coordinates of Determination; Asymmetric Cell Divisions and Asymmetric Fate; Generating Complexity through Cellular Interactions |
Specification and Differentiation through Cellular Interactions and Interactions with the Local EnvironmentCompetence and Histogenesis; The Interplay of Intrinsic and Extrinsic Influences in Histogenesis; Interpreting Gradients and the Spatial Organization of Cell Types; Summary; Chapter 5: Axon Growth and Guidance; The Growth Cone; The Dynamic Cytoskeleton; What Do Growth Cones Grow On?; What Provides Directional Information to Growth Cones?; Cell Adhesion and Labeled Pathways; Repulsive Guidance; Chemotaxis, Gradients, and Local Information; The Optic Pathway; The Midline |
Attraction and Repulsion: Desensitization and AdaptationSignal Transduction; Summary; Chapter 6: Target Selection; Defasiculation; Target Recognition and Entry; Slowing Down and Branching; Border Patrol and Prevention of Inappropriate Targeting; Topographic Mapping; Chemospecificity and Ephrins; Shifting and Fine Tuning of Connections; The Third Dimension, Lamina-Specific Termination; Cellular and Synaptic Targeting; Sniffing Out Targets; Summary; Chapter 7: Naturally Occurring Neuron Death; What does Neuron Death Look Like?; Early Elimination of Progenitor Cells |
How Many Differentiated Neurons Die? |
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Sommario/riassunto |
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Development of the Nervous System, Second Edition has been thoroughly revised and updated since the publication of the First Edition. It presents a broad outline of neural development principles as exemplified by key experiments and observations from past and recent times. The text is organized along a development pathway from the induction of the neural primordium to the emergence of behavior. It covers all the major topics including the patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, synapse formation and plasticity, and neuronal |
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