1.

Record Nr.

UNINA9910784253903321

Titolo

Molecular biology of spirochetes [[electronic resource] /] / edited by Felipe C. Cabello, Dagmar Hulinska, and Henry P. Godfrey

Pubbl/distr/stampa

Amsterdam ; ; Washington, D.C., : IOS Press, c2006

ISBN

1-280-70480-2

9786610704804

1-4294-5525-X

1-60750-202-X

600-00-0490-7

1-4337-0122-7

Descrizione fisica

1 online resource (416 p.)

Collana

NATO science series. Series I, Life and behavioural sciences, , 1566-7693  ; ; v. 373

Altri autori (Persone)

CabelloFelipe C. <1942->

HulinskaDagmar

GodfreyHenry P

Disciplina

579.3/2

Soggetti

Spirochetes

Molecular microbiology

Bacterial genetics

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

"Proceedings of the NATO Advanced Research Workshop on Molecular Biology of Spirochetes, Prague, Czech Republic"--T.p. verso.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Title page; Preface; Contents; Introductory Overview; Dissemination and Persistence are Pathogenic Events Common to All of the Major Human Spirochetal Infections; Molecular Genetics of Spirochetes; Transposon Mutagenesis of Infectious Borrelia burgdorferi B31: A Pilot Study; The Isolation and Characterization of Isogenic Mutants in Infectious Borrelia burgdorferi; Motility Gene Regulation and Chemotaxis in Borrelia burgdorferi; Targeted and Random Mutagenesis in Leptospira biflexa: Application for the Functional Analysis of Iron Transporters

Antibiotic Resistance in Borrelia burgdorferi: Applications for Genetic Manipulation and Implications for EvolutionDevelopment of Treponeme Genetic Systems; Genomics and Diversity; Comparative Genomics of Borrelia burgdorferi; Treponema Genomics; Comparative Analysis of



Pathogenic Leptospira Genomes; Leptospira interrogans: Genomics and ""Immunomics""; Genotypic Variation and Borrelia burgdorferi Pathogenesis; Multilocus Sequence Analysis (MLSA) as an Alternative to Whole DNA/DNA Hybridization (WDDH) in Borrelia burgdorferi sensu lato Taxonomy

Diversity and Variability of Protein-Encoding Genes of Borrelia burgdorferi sensu lato and Implications for Pathogenesis and Diagnosis of Lyme Borreliosis in EuropeAre Borrelia recurrentis and Borrelia duttonii the Same Spirochaete?; Genotyping of Borrelia burgdorferi sensu lato in Russia; Ecological and Genetic Diversity Within the Leptospiraceae Family: Implications for Epidemiology; Characterization of Borrelia burgdorferi sensu lato from Czech Patients and Ticks by Culture and PCR-Sequence Analysis

Infection of Ixodid Ticks, Mosquitoes and Patients with Borrelia, Bartonella, Rickettsia, Anaplasma, Ehrlichia and Babesia in Western Siberia, RussiaGene Expression; Genetic Studies of the Borrelia burgdorferi bmp Gene Family; Porins of Borrelia; Use of Green Fluorescent Protein Transcriptional Reporters to Study Differential Gene Expression by Borrelia burgdorferi; Regulation of Expression of the Integrin Ligand P66 in Borrelia burgdorferi; The Telomere Resolvase ResT and Evolution of the Borrelia Genomes; Hairpin Telomeres of Linear Bacterial Chromosomes and Plasmids: How to Make Them

Interactions of Spirochetes and HostsBlood-Induced Transcriptional Changes in Borrelia burgdorferi; Roles of Leptospiral Outer Membrane Proteins in Pathogenesis and Immunity; Genetic Analysis of Attachment of Borrelia burgdorferi to Host Cells and Extracellular Matrix; Borrelia burgdorferi and Ixodes scapularis: Exploring the Pathogen-Vector Interface; The Lyme Disease Spirochete Erp Protein Family: Structure, Function and Regulation of Expression; Lyme Disease Spirochetes Evade Innate Immunity by Acquisition of Complement Regulators, Factor H, and FHL-1

Outer Surface Lipoproteins of Borrelia burgdorferi: Role in Virulence, Persistence of the Pathogen, and in Protection Against Lyme Disease

Sommario/riassunto

Diseases produced by spirochetes, including Lyme borreliosis, syphilis and leptospirosis, are on the rise worldwide. This volume focuses on a series of state-of-the-art presentations of the research taking place in the laboratories of the contributors, and serves as an introduction to those individuals entering in the field of spirochete research.