1.

Record Nr.

UNINA9910784016903321

Titolo

The mouse in animal genetics and breeding research [[electronic resource] /] / Eugene J. Eisen [editor]

Pubbl/distr/stampa

London, : Imperial College Press

Hackensack, NJ ; ; London, : Distributed by World Scientific Pub. Co., c2005

ISBN

1-281-34751-5

9786611347512

1-86094-716-6

Descrizione fisica

1 online resource (376 p.)

Altri autori (Persone)

EisenEugene J

Disciplina

616/.027333

Soggetti

Mice - Genetics

Mice as laboratory animals

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

TABLE OF CONTENTS; PREFACE; CHAPTER 1 THE BEGINNINGS: ODE TO A WEE MOUSE; CHAPTER 2 TESTING QUANTITATIVE GENETIC SELECTION THEORY; CHAPTER 3 MATERNAL EFFECTS, GENOMIC IMPRINTING AND EVOLUTION; CHAPTER 4 INBREEDING AND CROSSBREEDING; CHAPTER 5 GENOTYPE BY ENVIRONMENT INTERACTION: LESSONS FROM THE MOUSE; CHAPTER 6 GENETICS OF GROWTH IN THE MOUSE; CHAPTER 7 GENETICS OF BODY COMPOSITION AND METABOLIC RATE; CHAPTER 8 GENETICS OF REPRODUCTION; CHAPTER 9 GENETICS AND BEHAVIOR; CHAPTER 10 GENETICS OF DISEASE RESISTANCE; CHAPTER 11 GENOMIC DISSECTION OF COMPLEX TRAIT PREDISPOSITION

CHAPTER 12 MOUSE MUTAGENESISCHAPTER 13 EMBRYO BIOTECHNOLOGIES; CHAPTER 14 TRANSGENICS; CHAPTER 15 THE MOUSE IN BIOMEDICAL RESEARCH; CHAPTER 16 THE MOUSE GENOME SEQUENCING PROJECT: AN OVERVIEW; Index

Sommario/riassunto

The sequencing of the mouse genome has placed the mouse front and center as the most important mammalian genetics model. However, no recent volume has detailed the genetic contributions the mouse has made across the spectrum of the life sciences; this book aims to fill



that vacuum. Mouse genetics research has made enormous contributions to the understanding of basic genetics, human genetics, and livestock genetics and breeding. The wide-ranging topics in the book include the mouse genome sequencing effort, molecular dissection of quantitative traits, embryo biotechnology, ENU mutagenesis, and