Pathophysiology and clinical applications of nitric oxide / / edited by Gabor M. Rubanyi

• Record Nr.: UNINA9910783978903321
• Pubbl/distr/stampa: Amsterdam : , : Harwood Academic Publishers, , 1990
• ISBN: 0-429-17673-2; 1-4822-8349-2; 1-280-05108-6; 9786610051083; 0-203-30372-5
• Descrizione fisica: 1 online resource (378 p.)
• Collana: Endothelial cell research series ; ; v. 5
• Altri autori (Persone): RubanyiGabor M. <1947->
• Disciplina: 612.01524
• Soggetti: Nitric oxide - Pathophysiology; Nitrogen compounds
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Book Cover; Half-Title; Title; Copyright; Dedication; Contents; Preface; Contributor; 13 Nitric Oxide and Its Role in Hemostasis; 14 Hypertension; 15 Pulmonary Hypertension; 16 Atherosclerosis: Role of NO; 17 Nitric Oxide in Myocardial and Splanchnic Ischemia/ Reperfusion; 18 Nitric Oxide and Circulatory Shock; 19 Kidney Diseases; 20 The Role of Nitric Oxide in Preterai Labour and Pre-eclampsia; 21 Multiple Sclerosis; 22 Regulation of Nitric Oxide and Inflammatory Mediators in Human Osteoarthritis-Affected Cartilage: Implication for Pharmacological Intervention; 23 The Role of Nitric Oxide in Rheumatoid Arthritis 24 Gastrointestinal Function in Shock; 25 Nitric Oxide Donors; 26 Nitric Oxide Inhalation; 27 Nitric Oxide Synthase Inhibitors; 28 The Pharmacology of Peroxynitrite-Dependent Neurotoxicity Blockade; 29 Hemoglobin: Its Role as a Nitric Oxide Scavenger; 30 Therapeutic Implications of Recombinant Endothelial Nitric Oxide Synthase Gene Expression in Cerebral and Peripheral Arteries; 31 Gene Therapy Approaches with iNOS Edith Tzeng and Timothy R.Billiar; Index
• Sommario/riassunto: Research on the key mediator nitric oxide has increased exponentially ; over the last ten years. It is now clear that, in addition to its role within the cardiovascular system, this mediator is also implicated in the normal physiological function and disease pathology of several organs and systems. A number of the fundamental research observations are now being developed into therapeutic principles and these are being pursued through clinical trials. This is the first work summarizing, in its two volumes, the quantum leap from basic science to clinical applications emerging from this decade of