1.

Record Nr.

UNINA9910783946603321

Titolo

Using CNS autopsy tissue in psychiatric research : a practical guide / / edited by Brian Dean, Joel E. Kleinman and Thomas M. Hyde

Pubbl/distr/stampa

Amsterdam : , : Harwood Academic Publishers, , 1999

ISBN

0-429-27124-7

1-4822-8341-7

1-280-07237-7

0-203-30427-6

9786610072378

Descrizione fisica

1 online resource (188 p.)

Altri autori (Persone)

DeanBrian, Dr.

HydeThomas M <1957-> (Thomas Michael)

KleinmanJoel E. <1945->

Disciplina

611.0188

Soggetti

Psychiatry - Research

Neuropsychiatry

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Book Cover; Title; Contents; Foreword; Contributors; The Collection of Tissue at Autopsy: Practical and Ethical Issues; Psychiatric Diagnosis After Death: The Problems of Accurate Diagnosis from Case History Review and Relative Interviews; Membrane Binding Assays: Membrane Preparation and Assay Development; The Localisation and Quantification of Molecular Changes in the Human Brain Using In Situ Radioligand Binding and Autoradiography; In Situ Hybridisation Histochemistry: Application to Human Brain Tissue; Immunohistochemistry Techniques Applicable for Use with Human Brain Tissue

The Processing and Use of Postmortem Human Brain Tissue for Electron MicroscopyIsolating Components of Human Brain: The Purification of A and the Alzheimer's Amyloid Precursor Protein; Analysis of Receptor Systems in Schizophrenia Using Tissue Obtained at Autopsy and Neuroimaging; Index

Sommario/riassunto

Essential for the laboratory, this practical manual presents a wide



variety of techniques associated with the use of human CNS tissue obtained at autopsy. The book contains detailed methodologies in discrete chapters written by an expert in the specific field. It also addresses the potential for extending molecular studies in brain tissue obtained at autopsy into studies in living brain by using neuroimaging techniques. In addition, the reader is directed to suppliers of equipment and reagents that have been shown to be useful when studying human brain tissue.

2.

Record Nr.

UNINA9910254238903321

Titolo

Innovative Numerical Approaches for Multi-Field and Multi-Scale Problems : In Honor of Michael Ortiz's 60th Birthday / / edited by Kerstin Weinberg, Anna Pandolfi

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016

ISBN

3-319-39022-8

Edizione

[1st ed. 2016.]

Descrizione fisica

1 online resource (VIII, 307 p. 108 illus., 22 illus. in color.)

Collana

Lecture Notes in Applied and Computational Mechanics, , 1613-7736 ; ; 81

Disciplina

620.10015118

Soggetti

Mechanics

Mechanics, Applied

Calculus of variations

Mathematical physics

Solid Mechanics

Calculus of Variations and Optimal Control; Optimization

Mathematical Applications in the Physical Sciences

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references at the end of each chapters.

Nota di contenuto

Robust Numerical Schemes for an Efficient Implementation of Tangent Matrices: Application to Hyperelasticity, Inelastic Standard Dissipative Materials and Thermo-Mechanics at Finite Strains -- Folding patterns in partially delaminated thin films -- Thermo-mechanical Behavior of Confined Granular Systems -- Elastomeric gels: a model and first



results -- A Tensegrity Paradigm for Minimal Mass Design of Roofs and Bridges -- Universal Meshes for the Simulation of Brittle Fracture and Moving Boundary Problems -- Free energy, free entropy, and a gradient structure for Thermoplasticity -- Comparison of isotropic elasto-plastic models for the plastic metric tensor Cp = FT p Fp  -- Quasi-static evolutions in brittle fracture generated by gradient flows: sharp crack and phase-field approaches -- Improving the Material-PointMethod -- Meshfree methods applied to consolidation problems in saturated Soils -- A multiscale microstructural model of permeability in fractured Solids -- Thermal diffusion in a polymer blend.

Sommario/riassunto

This book provides readers with a detailed insight into diverse and exciting recent developments in computational solid mechanics, documenting new perspectives and horizons. The topics addressed cover a wide range of current research, from computational materials modeling, including crystal plasticity, micro-structured materials, and biomaterials, to multi-scale simulations of multi-physics phenomena. Particular emphasis is placed on pioneering discretization methods for the solution of coupled non-linear problems at different length scales. The book, written by leading experts, reflects the remarkable advances that have been made in the field over the past decade and more, largely due to the development of a sound mathematical background and efficient computational strategies. The contents build upon the 2014 IUTAM symposium celebrating the 60th birthday of Professor Michael Ortiz, to whom this book is dedicated. His work has long been recognized as pioneering and is a continuing source of inspiration for many researchers. It is hoped that by providing a "taste" of the field of computational mechanics, the book will promote its popularity among the mechanics and physics communities.