1.

Record Nr.

UNINA9910783704403321

Titolo

Morphogenesis of endothelium / / edited by Werner Risau and Gabor M. Rubanyi

Pubbl/distr/stampa

Amsterdam, The Netherlands : , : Harwood Academic, , 2000

ISBN

0-429-17944-8

1-4822-8411-1

1-280-07336-5

0-203-30435-7

9786610073368

Descrizione fisica

1 online resource (312 p.)

Collana

Endothelial cell research series ; ; v. 8

Altri autori (Persone)

RisauWerner <1953-1998.>

RubanyiGabor M. <1947->

Disciplina

573.18

611.0187

Soggetti

Vascular endothelium

Morphogenesis

Blood-vessels - Growth

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Book Cover; Title; Contents; Tribute; Contributors; Structural, Biochemical and Functional Differentiation of the Vascular Endothelium; Endothelial Fenestrae and Fenestral Diaphragms; Adhesion Molecules in Endothelial Cells and their Role in Vascular Morphogenesis; Development of the Vascular Endothelium in Avian Embryos; Development of the Heart, Large Vessels and Coronary Vasculature; The Development of the Retinal Vasculature; Development of the Blood-Brain Barrier; Development and Growth of the Pulmonary Microvasculature; Development of the Kidney Vascular System

Development of the Liver Vascular SystemDevelopment of the Limb Bud Vascular System; Development of the Vascular System in Skeletal Muscle; Development of the Vascular System in the Corpus Luteum; Development of the Vascular System in the Placenta; The Development of the Lymph Node Vasculature; Index



Sommario/riassunto

The cardiovascular system is the first functional organ system to develop in the vertebrate embryo. Embryonic growth and differentiation essentially depend on transport of nutrients and waste through the early vasculature, and certain events in morphogenesis are thought to be influenced by the hemodynamic forces of the beating heart. The vasculature not only serves as a 'nutrient and waste pipeline' but is also a major communication system between distant organs and tissues. The vascular endothelial cell mediates vascular growth, permeability, integrity and interactions with blood cells. In mo

2.

Record Nr.

UNINA9910830572203321

Titolo

Applied biocatalysis : from fundamental science to industrial applications / / edited by Lutz Hilterhaus [and three others]

Pubbl/distr/stampa

Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Co. KGaA, , 2016

©2016

ISBN

3-527-67714-3

3-527-67713-5

3-527-67712-7

Descrizione fisica

1 online resource (464 p.)

Disciplina

660.634

Soggetti

Enzymes - Biotechnology

Biocatalysis

Enzymes - Industrial applications

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references at the end of each chapters and index.

Nota di contenuto

Cover; Title Page; Copyright; Contents; List of Contributors; Preface; Part A Molecular Biology, Enzyme Screening and Bioinformatics; Part B Biocatalytic Synthesis; Part C Reaction and Process Engineering; Index; EULA; Chapter 1 Engineering Lipases with an Expanded Genetic Code; Chapter 2 Screening of Enzymes: Novel Screening Technologies to Exploit Noncultivated Microbes for Biotechnology; Chapter 3 Robust



Biocatalysts - Routes to New Diversity; Chapter 4 Application of High-Throughput Screening in Biocatalysis; Chapter 5 Supporting Biocatalysis Research with Structural Bioinformatics

Chapter 6 Engineering Proteases for Industrial ApplicationsChapter 7 Biocatalytic Synthesis of Natural Products by O-Methyltransferases; Chapter 8 Biocatalytic Phosphorylation of Metabolites; Chapter 9 Flavonoid Biotechnology - New Ways to High-Added-Value Compounds; Chapter 10 Transaminases - A Biosynthetic Route for Chiral Amines; Chapter 11 Biocatalytic Processes for the Synthesis of Chiral Alcohols; Chapter 12 Inorganic Adsorbents in Enzymatic Processes; Chapter 13 Industrial Application of Membrane Chromatography for the Purification of Enzymes

Chapter 14 Fermentation of Lactic Acid Bacteria: State of the Art and New PerspectivesChapter 15 The Bubble Column Reactor: A Novel Reactor Type for Cosmetic Esters; Chapter 16 Pharmaceutical Intermediates by Biocatalysis: From Fundamental Science to Industrial Applications; Chapter 17 Biocatalysis toward New Biobased Building Blocks for Polymeric Materials; 1.1 Introduction; 1.2 Enzyme Activity of Lipases from Different Sources and Engineering Approaches; 1.3 Noncanonical Amino Acids in Lipase Design and Engineering

1.4 Case Study: Manipulating Proline, Phenylalanine, and Methionine Residues in Lipase1.5 ""Unnatural"" Lipases Are Able to Catalyze Reactions under Different Hostile Environments; 1.6 Lipase Engineering via Bioorthogonal Chemistries: Activity and Immobilization; 1.7 Conclusions and Perspectives; References; 2.1 Introduction; 2.2 Sequence- versus Function-Based Metagenomic Approach to Find Novel Biocatalysts; 2.3 Alternative Hosts, Metatranscriptomics, and Metaproteomics; 2.4 Future Perspectives; References; 3.1 Introduction

3.2 Metagenomics to Retrieve New Genes from Extremophilic Microorganisms3.3 Microbial Expression Hosts for the Production of Extremozymes; 3.4 Molecular Biology Approaches for Enzyme Improvement; 3.5 Conclusions and Future Perspectives; References; 4.1 Introduction; 4.2 Discussions; 4.3 Summary; References; 5.1 Introduction; 5.2 Computational Tools to Assist Biocatalysis Research; 5.3 From Active Site Analysis to Protein Stability Considerations; 5.4 Applying DoGSiteScorer and HYDE to Biocatalytical Questions; 5.5 Conclusion and Future Directions; Acknowledgments; References

6.1 Proteases in Industry