1.

Record Nr.

UNINA9910450066503321

Autore

Nagel Thomas

Titolo

Concealment and exposure [[electronic resource] ] : and other essays / / Thomas Nagel

Pubbl/distr/stampa

New York ; ; Oxford, : Oxford University Press, 2002

ISBN

9786610501977

0-19-803489-X

1-282-36739-0

1-280-50197-9

9786612367397

1-4237-2222-1

Descrizione fisica

1 online resource (253 p.)

Disciplina

100

Soggetti

Philosophy of mind

Ethics, Modern

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Originally published: 2002.

Includes index.

Sommario/riassunto

Thomas Nagel is widely recognized as one of the top American philosophers working today. Reflecting the diversity of his many philosophical preoccupations, this volume is a collection of his most recent critical essays and reviews. The first section, Public and Private, focuses on the notion of privacy in the context of social and political issues, such as the impeachment of President Clinton. The second section, Right and Wrong, discusses moral, political and legal theory, and includes pieces on John Rawls, G.A. Cohen, and T.M. Scanlon, among others. The final section, Mind and Reality, features discussions of Richard Rorty, Donald Davidson, and the Sokal hoax, and closes with a substantial new essay on the mind-body problem. Written with characteristic rigor, these pieces reveal the intellectual passion underlying the incisive analysis for which Nagel is known.



2.

Record Nr.

UNINA9910783131603321

Autore

Mansour Tag E.

Titolo

Chemotherapeutic targets in parasites : contemporary strategies / / Tag E. Mansour ; with the assistance of Joan MacKinnon Mansour [[electronic resource]]

Pubbl/distr/stampa

Cambridge : , : Cambridge University Press, , 2002

ISBN

1-107-12776-9

1-280-41736-6

9786610417360

1-139-14566-5

0-511-18051-9

0-511-06598-1

0-511-05967-1

0-511-30742-X

0-511-54644-0

0-511-06811-5

Descrizione fisica

1 online resource (xiv, 226 pages) : digital, PDF file(s)

Disciplina

616.9/6061

Soggetti

Antiparasitic agents

Parasitic diseases - Chemotherapy

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Title from publisher's bibliographic system (viewed on 05 Oct 2015).

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Cover; Half-title; Title; Copyright; Contents; Preface; Acknowledgments; 1 The Search for Antiparasitic Agents; 2 Biophysical, Genomic, and Proteomic Analysis of Drug Targets; 3 Energy Metabolism in Parasitic Helminths; 4 Antimalarial Agents and Their Targets; 5 Antitrypanosomal and Antileishmanial Targets; 6 Targets in Amitochondrial Protists; 7 Neuromuscular Structures and Microtubules as Targets; 8 Targets in the Tegument of Flatworms; Epilogue; Index

Sommario/riassunto

Parasitic infections are the most prevalent of human diseases, and researchers continue to face the challenge of designing drugs to successfully counteract them. Chemotherapeutic Targets in Parasites analyzes the critical metabolic reactions and structural features



essential for parasite survival, and advocates the latest molecular strategies with which to identify effective antiparasitic agents. An introduction to the early development of parasite chemotherapy is followed by an overview of biophysical techniques and genomic and proteomic analysis. Several chapters are devoted to specific types of chemotherapeutic agents and their targets in malaria, trypanosomes, leishmania and amitochondrial protists. Chapters on helminths include metabolic, neuromuscular, microtubular and tegumental targets. Emphasized throughout is the design of more selective and less toxic drugs than in the past. This book will be especially relevant to medical and clinical researchers and to graduate students in parasitology, pharmacology, medicine, microbiology, and biochemistry.