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1. |
Record Nr. |
UNINA9910144273203321 |
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Titolo |
Chirality in drug research [[electronic resource] /] / edited by Eric Francotte and Wolfgang Lindner |
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Pubbl/distr/stampa |
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Weinheim, : Wiley-VCH, c2006 |
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ISBN |
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1-281-08787-4 |
9786611087876 |
3-527-60943-1 |
3-527-60871-0 |
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Descrizione fisica |
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1 online resource (373 p.) |
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Collana |
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Methods and principles in medicinal chemistry ; ; v. 33 |
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Altri autori (Persone) |
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FrancotteEric |
LindnerW (Wolfgang) |
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Disciplina |
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Soggetti |
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Chiral drugs |
Drugs - Research |
Drug development |
Médicaments - Recherche |
Médicaments - Développement |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Chiral drugs from a historical point of view / Joseph Gal -- Stereoselective synthesis of drugs : an industrial perspective / Hans-Jürgen Federsel -- Aspects of chirality in natural products drug discovery / Philipp Krastel, Frank Petersen, Silvio Roggo, Esther Schmitt, Ansgar Schuffenhauer -- Biotransformation methods for preparing chiral drugs and drug intermediates / Michael Müller, Marcel Wubbolts -- Resolution of chiral drugs and drug intermediates by crystallisation / Kazuhiko Saigo and Kenichi Sakai -- Isolation and production of optically pure drugs by enantioselective chromatography / Eric Francotte -- Stereoselective chromatographic methods for drug analysis / Norbert M. Maier, Wolfgang Lindner -- Capillary electrophoresis coupled to mass spectrometry for chiral drugs analysis / Serge Rudaz, Jean-Luc Veuthey -- Powerful chiral molecular tools for |
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preparation of enantiopure alcohols and simultaneous determination of their absolute configurations by X-ray crystallography and/or p1 sH NMR anisotropy methods / Nobuyuki Harada -- Keywords in chirality modeling : molecular modeling of chirality : software and literature research on chirality in modeling, chirality in docking, chiral ligand-receptor interaction and symmetry / Gerd Folkers, Mine Yarim, Pavel Pospisil. |
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Sommario/riassunto |
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Divided into the three main sections of synthesis, analysis and drug development, this handbook covers all stages of the drug development process, including large-scale synthesis and purification of chirally pure pharmaceuticals. The two editors from academia and a major pharmaceutical company have assembled an experienced, international team who provide first-hand practical advice and report previously unpublished data.In the first section, the isolation of chiral drugs from natural sources, their production in enzymatic processes and the resolution of racemic mixtures in preparative |
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2. |
Record Nr. |
UNINA9910782561703321 |
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Autore |
Colman Tyler |
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Titolo |
Wine politics [[electronic resource] ] : how governments, environmentalists, mobsters, and critics influence the wines we drink / / Tyler Colman |
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Pubbl/distr/stampa |
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Berkeley, : University of California Press, c2008 |
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ISBN |
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1-281-75268-1 |
1-4356-8478-8 |
9786611752682 |
0-520-93473-3 |
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Descrizione fisica |
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1 online resource (206 p.) |
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Disciplina |
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Soggetti |
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Wine - Political aspects |
Wine industry |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references (p. 167-172) and index. |
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Nota di contenuto |
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What is wine politics? -- Soil and society -- Authenticating origins -- Baptists and bootleggers -- Who controls your palate? -- Greens, grapes, and gripes -- Celebrating diversity. |
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Sommario/riassunto |
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After reading this intriguing book, a glass of wine will be more than hints of blackberries or truffles on the palate. Written by the author of the popular, award-winning website DrVino.com, Wine Politics exposes a little-known but extremely influential aspect of the wine business-the politics behind it. Tyler Colman systematically explains how politics affects what we can buy, how much it costs, how it tastes, what appears on labels, and more. He offers an insightful comparative view of wine-making in Napa and Bordeaux, tracing the different paths American and French wines take as they travel from vineyard to dining room table. Colman also explores globalization in the wine business and illuminates the role of behind-the-scenes players such as governments, distributors, and prominent critics who wield enormous clout. Throughout, Wine Politics reveals just how deeply politics matters- right down to the taste of the wine in your glass tonight. |
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