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1. |
Record Nr. |
UNINA9910782042703321 |
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Titolo |
Assessment of the scientific information for the Radiation Exposure Screening and Education Program [[electronic resource] /] / Committee to Assess the Scientific Information for the Radiation Exposure Screening and Education Program, Board on Radiation Effects Research, Division on Earth and Life Studies |
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Pubbl/distr/stampa |
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Washington, D.C., : National Academies Press, 2005 |
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ISBN |
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0-309-16514-8 |
1-280-74214-3 |
9786610742141 |
0-309-54931-0 |
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Descrizione fisica |
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1 online resource (429 p.) |
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Disciplina |
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Soggetti |
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Nuclear weapons - United States - Testing |
Radiation dosimetry |
Radiation - Physiological effect - Research - United States |
Radiation - Safety measures |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references. |
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Nota di contenuto |
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""Front Matter""; ""Acknowledgments""; ""Reviewers""; ""A Note on the Units of Measurement Used in this Report""; ""Contents""; ""Executive Summary""; ""1 Introduction""; ""2 Legislation and Compensation""; ""3 Basic Concepts in Radiation Physics, Biology, and Epidemiology""; ""4 Review of Recent Data on Radiation Epidemiology, Biology, and Dosimetry""; ""5 Expanding RECA Eligibility: Scientific Issues""; ""6 Expanding RECA Eligibility: Implementation""; ""7 Diseases, Populations, and Other Issues of Public Concern""; ""8 Ethical Framework""; ""9 Medical Screening"" |
""10 Screening for Compensation""""11 Education and Outreach""; ""References""; ""Appendixes""; ""Appendix A Invited Speakers and Public Comment""; ""Appendix B A Comparison of the Risk of Skin Cancer with the Risk of Lung Cancer from Exposure to Radon Decay Products in Underground Mines""; ""Appendix C Radioactivity in Guam |
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After Nuclear- Weapons Testing in the Pacific""; ""Appendix D The Optimal Criterion for Positivity in Screening""; ""Appendix E Selected Cancer-Screening Recommendations""; ""Glossary""; ""List of Abbreviations""; ""Committee and Staff Biographies"" |
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2. |
Record Nr. |
UNINA9910253921503321 |
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Titolo |
Behavioral Neuroscience of Orexin/Hypocretin / / edited by Andrew J Lawrence, Luis de Lecea |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
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ISBN |
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Edizione |
[1st ed. 2017.] |
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Descrizione fisica |
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1 online resource (VIII, 322 p. 30 illus., 22 illus. in color.) |
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Collana |
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Current Topics in Behavioral Neurosciences, , 1866-3370 ; ; 33 |
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Disciplina |
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Soggetti |
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Neurosciences |
Pharmacology |
Psychopharmacology |
Behavioral sciences |
Neurology |
Pain medicine |
Pharmacology/Toxicology |
Behavioral Sciences |
Pain Medicine |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references at the end of each chapters. |
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Nota di contenuto |
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The Human Orexin/Hypocretin Receptor Crystal Structures -- Orexin/Hypocretin Signaling -- Orexin/Hypocretin and Organizing Principles for a Diversity of Wake-Promoting Neurons in the Brain -- The Hypocretin/Orexin Neuronal Networks in Zebrafish -- Hypocretins and Arousal -- Orexin OX 2 Receptor Antagonists as Sleep Aids -- Roles for Orexin/Hypocretin in the Control of Energy Balance and Metabolism -- Orexin and Central Modulation of Cardiovascular and Respiratory Function -- Role of the Orexin/Hypocretin System in Stress-Related Psychiatric Disorders -- The Role of |
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Orexins/Hypocretins in Alcohol Use and Abuse -- A Decade of Orexin/Hypocretin and Addiction: Where Are We Now?- Hypocretin/Orexin and Plastic Adaptations Associated with Drug Abuse. |
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Sommario/riassunto |
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This issue of Current Topics in Behavioral Neuroscience focuses on the neuropeptide orexin (hypocretin) and brings together scientists from around the world who will provide a timely discussion of how this peptide regulates behavior. This is a fast-moving field, and with the incorporation of novel technologies, new breakthroughs are likely to continue. For example, the use of optogenetic approaches has enabled the identification of the role of orexin-containing neurons in arousal states, critical for higher order functioning. From a clinical perspective, genetic polymorphisms in hypocretin/orexin and orexin receptors are implicated in a number of psychiatric disorders. In addition, advanced clinical trials are currently underway for orexin receptor antagonists in the treatment of insomnia and sleep disorders. We aim to capture a broad audience of basic scientists and clinicians. |
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