1.

Record Nr.

UNINA9910139564303321

Autore

Adinoff Bryon

Titolo

Neuroimaging in addiction [[electronic resource] /] / Bryon Adinoff and Elliot Stein

Pubbl/distr/stampa

Chichester, West Sussex, : John Wiley & Sons, 2011

ISBN

1-283-33323-6

9786613333230

1-119-97270-1

1-119-99893-X

1-119-99846-8

Descrizione fisica

1 online resource (373 p.)

Altri autori (Persone)

SteinElliot

Disciplina

616.8

616.8047572

Soggetti

Brain - Effect of drugs on

Brain - Radiography

Compulsive behavior - Magnetic resonance imaging

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Neuroimagingin Addiction; Contents; Foreword; List of Contributors; 1 Introduction; 2 An Integrated Framework for Human Neuroimaging Studies of Addiction from a Preclinical Perspective; 2.1 Introduction; 2.2 A Conceptual Framework for Understanding Drug Addiction Based on Preclinical Observations; 2.3 Neuropharmacological Considerations; 2.4 Neuropathology of Chronic Drug Abuse; 2.5 Impulsivity: An Endophenotype for Drug Addiction; 2.6 Compulsivity: Craving versus Drug-Seeking; 2.7 Summary; References

3 Structural and Functional Neuroimaging Methods: Applications to Substance Abuse and Addiction3.1 Introduction; 3.2 MRI Based Imaging Tools and their Application to Drug Abuse Research; 3.3 Molecular Imaging with PET and SPECT; 3.4 Summary and Peek into the Future; References; 4 Functional Neuroimaging of the Acute Effects of Drugs of Abuse; 4.1 Introduction; 4.2 Fundamental Neuronal Systems Related to Abuse Liability in Humans; 4.3 Psychostimulants; 4.4 Alcohol; 4.5 Cannabis and the Cannabinoids; 4.6 Opioids; 4.7 Conclusions and



Future Directions; References; 5 Reward Processing

5.1 Introduction5.2 Neurotransmitter Systems Implicated in Reward Processing; 5.3 Neurotransmitter Systems Involved in Drug-Related Reward Processing; 5.4 Alterations in the Mesostriatal System in Addiction; 5.5 Summary and Outlook; 5.6 Acknowledgments; References; 6 A Neuroimaging Approach to the Study of Craving; 6.1 A Neuroimaging Approach to the Study of Craving; 6.2 Neural Response During Cue-Elicited Craving; 6.3 Associations between Neural and Subjective Response During Cue-Elicited Craving; 6.4 Modulators of Neural Response During Cue-Elicited Craving

6.5 Effects of Intervention on the Neural Response During Cue-Elicited Craving6.6 Summary and Integration of Findings; 6.7 Conclusions; References; 7 Impulsivity and Addiction; 7.1 Introduction; 7.2 Impulsivity as Reward versus Control; 7.3 The Neurobiology of Impulsivity; 7.4 Impulsivity and Risk for Developing a Drug Use Disorder; 7.5 Impulsivity in Current Users; 7.6 Impulsivity, Abstinence, and Relapse; 7.7 Conclusion; References; 8 Cognitive Disruptions in Drug Addiction: a Focus on the Prefrontal Cortex; 8.1 Introduction; 8.2 Attention; 8.3 Working Memory; 8.4 Decision-Making

8.5 Pre-Morbid Vulnerabilities8.6 Other Brain Regions; 8.7 Limitations Across All Studies; 8.8 Treatment Implications; 8.9 General Summary and Conclusions; 8.10 Acknowledgments; References; 9 Neural Mechanisms of Stress and Addiction; 9.1 Stress and Addiction; 9.2 Neural Circuits of Stress Regulation; 9.3 Dysfunction in the Neural Circuits Underlying Stress and Addiction; 9.4 Interplay of Gene, Stress, and Drug Intake; 9.5 Acknowledgments; References; 10 Anatomical and Neurochemical Evidence of Neurotoxic Changes in Psychostimulant Abuse and Dependence; 10.1 Introduction

10.2 Characteristics of Psychostimulants

Sommario/riassunto

Neuroimaging in Addiction presents an up-to-date, comprehensive review of the functional and structural imaging human studies that have greatly advanced our understanding of this complex disorder. Approaching addiction from a conceptual rather than a substance-specific perspective, this book integrates broad neuropsychological constructs that consider addiction as a neuroplastic process with genetic, developmental, and substance-induced contributions. The internationally recognized contributors to this volume are leaders in clinical imaging with expertise that spans the addiction spec



2.

Record Nr.

UNINA9910780939803321

Autore

Pellissier Hélène

Titolo

Recent developments in asymmetric organocatalysis [[electronic resource] /] / Hélène Pellissier

Pubbl/distr/stampa

Cambridge, : RSC Pub., 2010

ISBN

1-84973-114-4

Descrizione fisica

1 online resource (258 p.)

Collana

RSC catalysis series, , 1757-6725 ; ; no. 3

Disciplina

547.2/15

547.215

Soggetti

Asymmetric synthesis

Catalysis

Organic compounds - Synthesis

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Recent Developments in Asymmetric Organocatalysis_Publicity; i_iv; v_viii; ix_xii; xiii_xvi; 001_076; 077_122; 123_149; 150_157; 158_171; 172_191; 192_201; 202_212; 213_219; 220_231; 232_233; 234_241

Sommario/riassunto

The aim of this book is to cover the very recent developments in asymmetric organocatalysis, focussing on those published since the beginning of 2008. The last decade has witnessed an explosive growth in the field of asymmetric organocatalysis with an impressive amount of new catalysts, novel methodologies, and applications in numerous reaction types, such as nucleophilic substitutions, addition reactions, as well as cycloadditions, oxidations, reductions, kinetic resolutions, and miscellaneous reactions. This very diverse and intensely developing field is too wide to cover in a single review.