1.

Record Nr.

UNINA9910524661303321

Autore

Thompson Mark L.

Titolo

Steamboats and Sailors of the Great Lakes / / Mark L. Thompson

Pubbl/distr/stampa

Detroit : , : Wayne State University Press, , 2017

Descrizione fisica

1 online resource (231 pages) : illustrations

Collana

Great Lakes Books Series

Disciplina

387.24

Soggetti

Steamboats - History

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

The Great Lakes shipping industry can trace its lineage to 1679 with the launching on Lake Erie of the Griffon, a sixty-foot galley weighing nearly fifty tons. Built by LaSalle, a French explorer who had been commissioned to search for a passage through North America to China, it was the first sailing ship to operate on the upper lakes, signaling the dawn of the Great Lakes shipping industry as we know it today. Steamboats and Sailors of the Great Lakes is the most thorough and factual study of the Great Lakes shipping industry written this century. Author Mark L. Thompson tells the fascinating story of the world's most efficient bulk transportation system, describing the Great Lakes freighters, the cargoes of the great ships, and the men and women who have served as crew. He documents the dramatic changes that have taken places in the industry and looks at the critical role that Great Lakes shipping plays in the economic well-being of the U.S. and Canada, despite the fact tat the size of the fleet and the amount of cargo carried have declined dramatically in recent years. Spanning more than three centuries, from LaSalle's voyage in 1679, through 1975 with the mysterious sinking of the Edmund Fitzgerald, to life aboard today's thousand-foot behemoths, this important volume documents the evolution of the industry through its "Golden Age" at the end of the nineteenth century to the present, with a downsized U.S. fleet that numbers fewer than seventy vessels.



2.

Record Nr.

UNINA9910779646103321

Titolo

Telomeres [[electronic resource] ] : function, shortening and lengthening / / Leonardo Mancini, editor

Pubbl/distr/stampa

New York, : Nova Biomedical Books, c2009

ISBN

1-60876-720-5

Descrizione fisica

1 online resource (498 p.)

Altri autori (Persone)

ManciniLeonardo

Disciplina

572.8/7

Soggetti

Telomere

Telomerase

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Telomere dynamics and biology in human progeroid syndromes / Terence Davis, Hannah S.E. Tivey, and David Kipling -- The role of telomere-telomerase system in age-related fitness decline : a tameable process / Giacinto Libertini -- Cytogenetic evaluation of telomere dysfunction : chromosomal aberrations involving telomeres and interstitial telomeric sequences / Alejandro D. Bolzán -- Telomeres-telomerase biology and their role in renal and other chronic diseases / Kordinas Vasileios ... [et al.] -- Telomerase and telomere dynamics in cancer : clinical application for cancer diagnosis / Eiso Hiyama, Keiko Hiyama -- Telomeres and chromosome segregation / Antonella Sgura and Daniela Cimini -- Telomere-based genome-protective responses : a mammalian improvement on the bacterial SOS response? / Barbara A. Gilchrest, Mark S. Eller -- Telomere lengthening from oocyte to embryonic stem cell / Eva Pericuesta ... [et al.] -- Transcriptional activity at the telomeres of chironomus (diptera) : its possible role in the lengthening of the telomeres / J.L. Diez ... [et al.] --

Telomerase activity : application to diagnosis of human carcinoma / Liliana N. Guerra -- Telomere shortening in diabetes mellitus / Nicholas Tentolouris, Athanasia Papazafiropoulou -- Do alterations in the three-dimensional organization of telomeres indicate malignant transformation? / Sandrine Lacoste, Hans Knecht, and Sabine Mai -- Telomeres : function, shortening and lengthening / Barry Flanary -- Telomerase regulation in stem cells : how to flip the switch? / Rich



Allsopp -- Telomere maintenance mechanisms in bone and soft tissue tumors / Toshihiro Matsuo ... [et al.] -- Genetic polymorphisms of human telomerase reverse transcriptase (hTERT) : mini review / Yumiko Matsubara, Mitsuru Murata, and Yasuo Ikeda -- Genetic inhibition of telomere lengthening in cancer prevention and treatment / F. Mathias Bollmann -- Telomeres : function, shortening, and lengthening / Barry Flanary -- Clinical implications of telomerase activity in human brain tumors / Hyoung-Joon Chun ... [et al.].