Review of the Hanford thyroid disease study draft final report [[electronic resource] /] / Committee on an Assessment of Centers for Disease Control and Prevention Radiation Studies from DOE Contractor Sites ; Subcommittee to Review the Hanford Thyroid Disease Study Final Results and Report, Board on Radiation Effects Research, Commission on Life Sciences, National Academy of Sciences

• Record Nr.: UNINA9910778641503321
• Pubbl/distr/stampa: Washington, D.C., : National Academy Press, 2000
• ISBN: 1-280-18559-7; 9786610185597; 0-309-57146-4; 0-585-21934-6
• Descrizione fisica: 1 online resource (228 p.)
• Disciplina: 614.5/944/00979751
• Soggetti: Thyroid gland - Diseases - Epidemiology - Research - Washington (State) - Methodology; Thyroid gland - Diseases - Epidemiology - Research - Oregon - Methodology; Ionizing radiation - Toxicology - Washington (State); Ionizing radiation - Toxicology - Oregon; Hanford Site (Wash.)
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references.
• Nota di contenuto: ""Review of the Hanford Thyroid Disease Study Draft Final Report""; ""Copyright""; ""ACKNOWLEDGEMENTS""; ""Contents""; ""Public Summary""; ""BACKGROUND""; ""DESIGN OF THE HTDS""; ""Estimated Radiation Exposures""; ""Analysis of HTDS Data""; ""Statistical Power and the HTDS Interpretation""; ""Communication of HTDS Results to the Public""; ""Concluding Remarks""; ""Executive Summary""; ""BACKGROUND""; ""EPIDEMIOLOGIC AND CLINICAL METHODS AND DATA COLLECTION""; ""Conclusions:""; ""Recommendations:""; ""DOSIMETRY""; ""Conclusions:""; ""Recommendations:""; ""STATISTICAL ANALYSES""; ""Conclusions:""""Recommendations:""; ""STATISTICAL POWER AND INTERPRETATION OF THE STUDY""; ""Conclusions:""; ""Recommendations:""; ""COMMUNICATION OF THE STUDY RESULTS TO THE PUBLIC""; ""Conclusions:""; ""Recommendations:""; ""SUMMARY OF RESPONSES TO THE CDC'S QUESTIONS""; ""1 Introduction ""; ""2 Overview of the HTDS Draft Final Report and Organization of the Committee's Report ""; ""3 Evaluation of Epidemiologic and Clinical Methods ""; ""EVALUATION OF EPIDEMIOLOGIC METHODS""; ""MILK-CONSUMPTION ESTIMATION""; ""EVALUATION OF CLINICAL-DATA COLLECTION""; ""COMPLETENESS OF ASCERTAINMENT OF THYROID DISEASE""""SUSCEPTIBILITY FACTORS FOR THYROID DISEASE""; ""EVALUATION OF MORTALITY DATA""; ""AMERICAN INDIAN TRIBAL ISSUES""; ""4 Evaluation of Dosimetric Methods and Results ""; ""BACKGROUND""; ""HEDR CALCULATIONS OF ENVIRONMENTAL CONCENTRATIONS OF 131 I FROM HANFORD AND RESULTING DOSES: ASSESS ME...""; ""Source Term:""; ""Concentration of 131 I in Pasture Grass at Time of Fallout:""; ""Mean Time of Residence of 131I on Pasture Grass:""; ""Pasture Intake by Cows:""; ""Transfer Coefficient of 131I from Cow's Intake to Milk:""; ""Milk-Distribution Factor:""""Milk-Consumption Rate:""; ""Thyroid Dose Coefficient:""; ""HEDR DOSIMETRY-MODEL VALIDATION""; ""Thyroid Burdens""; ""Milk Concentrations""; ""Concentrations in Vegetation""; ""Concentrations in Air""; ""Conclusions""; ""Possible Underestimation or Overestimation of Doses""; ""DOSE UNCERTAINTIES""; ""131 I FROM THE NEVADA TEST SITE AND GLOBAL FALLOUT""; ""OTHER SOURCES OF RADIATION EXPOSURE""; ""5 Evaluation of Statistical Data Analysis ""; ""MODE OF PRESENTATION OF RESULTS""; ""TYPES OF ANALYSES AND RELATED DOSIMETRY-ERROR ISSUES""; ""ANALYSIS OF POTENTIAL CONFOUNDING OR EFFECT-MODIFYING VARIABLES""""ASSUMPTION OF EQUIVALENT RADIATION EFFECT FOR MALES AND FEMALES""; ""ANALYSES BY AGE AT EXPOSURE""; ""OUT-OF-AREA ANALYSES""; ""GEOSTRATUM VERSUS DISEASE""; ""GENERAL-POPULATION COMPARISON AND SCREENING ISSUES""; ""ANALYSES OF SOURCE OF PERSONAL-EXPOSURE INFORMATION""; ""6 Statistical Power and Interpretation of the Study ""; ""FACTORS IN STATISTICAL POWER""; ""SAMPLE SIZE AND ASSUMED BACKGROUND PREVALENCE OF DISEASE""; ""EFFECT OF DOSIMETRY ERROR ON STATISTICAL POWER""; ""VIOLATION OF THE BERKSON ERROR ASSUMPTION""; ""DOSE ERROR DUE TO UNCERTAINTIES IN INPUT DATA""