Microbial status and genetic evaluation of mice and rats : proceedings of the 1999 US/Japan conference / / International Committee of the Institute for Laboratory Animal Research ; National Research Council

• Record Nr.: UNINA9910778633003321
• Pubbl/distr/stampa: Washington, D.C. : , : National Academy Press, , 2000; ©2000
• ISBN: 0-309-17147-4; 0-309-51351-0
• Descrizione fisica: 1 online resource (xv, 150 pages) : illustrations
• Collana: The compass series
• Disciplina: 636.088
• Soggetti: Rats as laboratory animals - Microbiology; Mice as laboratory animals - Microbiology; Rats - Diseases; Mice - Diseases; Rats - Breeding; Mice - Breeding
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Nota di bibliografia: Includes bibliographical references.
• Nota di contenuto: ""Front Matter""; ""Preface""; ""Contents""; ""Opening Remarks""; ""Introductory Comments on Microbiologic Testing of Laboratory Mice and Rats: Uniformity of Results""; ""Development of a Performance Assessment Program for Research Animal Diagnostic Laboratories and Defining Microbiologic Testing Standards""; ""Standardization of Rodent Health Surveillance: Regulation Versus Competition""; ""Factors Causing Difficulties in Uniformity of Results Among Testing Facilities in Microbiologic Monitoring of Laboratory Animals""; ""Necessity of Reexamining the Pathogenicity and Elimination of Parasites in Rats and Mice""; ""Emerging (and Reemerging) Viruses of Laboratory Mice and Rats""; ""Emerging Infections as a Cause of Concern""; ""Emerging Diseases in Mice and Rats""; ""Survey of Helicobacter Species in Laboratory Mice and Gerbils in Japan""; ""Genetic Evaluation of Outbred Rats""; ""Genetic Evaluation of Outbred Rats from the Breeder's Perspective""; ""Concept for Establishment of ; Rat Outbred Global Standard Strains""; ""Necessity of Genetic and Microbiologic Quality Network from the Pharmaceutical Industry's Perspective"""; "International Harmonization of Laboratory Animals""; ""Rat Genetics and Toxicology""; ""A Phenotype-driven Approach to the Molecular and Functional Analysis of the Mouse Genome""; ""Evaluation of Targeted Mutations""; ""Defining Behavioral Phenotypes in Transgenic and Knockout Mice""; ""Defining Phenotype in Genetically Engineered Mice""; ""Development of the Mouse Model Dramatype for Human Clinical Benefit""; ""Concluding Remarks""; ""Implication of Wild-derived Genes, Mitochondria, and Chromosomes in the Genetic Background of Mouse Models for Diseases and Biologic Functions""; ""Concluding Comments""; ""Concluding Comments""; ""Appendix A U.S./Japan Meeting November 15, 1999 Agenda""; ""Appendix B Meeting Participants""