Acute exposure guideline levels for selected airborne chemicals [[electronic resource] /] / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council

• Record Nr.: UNINA9910778610303321
• Pubbl/distr/stampa: Washington, D.C., : National Academy Press, c2000
• ISBN: 0-309-18354-5; 1-280-18513-9; 9786610185139; 0-309-56508-1
• Descrizione fisica: 1 online resource (219 p.)
• Collana: The compass series
• Disciplina: 615.9/1
• Soggetti: Gases, Asphyxiating and poisonous; Hazardous substances - Environmental aspects; Hazardous substances - Health aspects; Chemicals - Physiological effect; Chemicals - Health aspects
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references.
• Nota di contenuto: ""Acute Exposure Guideline Levels for Selected Airborne Chemicals""; ""Copyright""; ""Preface""; ""Contents""; ""Acute Exposure Guideline Levels for Selected Airborne Chemicals""; ""Introduction""; ""SUMMARY OF REPORT ON GUIDELINES FOR DEVELOPING AEGLS""; ""REVIEW OF AEGL REPORTS""; ""REFERENCES""; ""Roster of the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances""; ""COMMITTEE MEMBERS""; ""OAK RIDGE NATIONAL LABORATORY STAFF""; ""NATIONAL ADVISORY COMMITTEE STAFF""; ""Appendix""; ""1 Aniline1 Acute Exposure Guideline Levels""; ""SUMMARY""; ""1. INTRODUCTION""""2. HUMAN TOXICITY DATA""; ""2.1. Acute Lethality""; ""2.2. Nonlethal Toxicity""; ""2.2.1. Experimental Studies""; ""2.2.2. Epidemiology Studies""; ""2.2.3. Accidents""; ""2.3. Developmental and Reproductive Effects""; ""2.4. Genotoxicity""; ""2.5. ; Carcinogenicity""; ""2.6. Summary""; ""3. ANIMAL TOXICITY DATA""; ""3.1. Acute Lethality""; ""3.1.1. Rats""; ""3.1.2. Mice""; ""3.2. Nonlethal Toxicity""; ""3.2.1. Dogs""; ""3.2.2. Rats""; ""3.2.3. Mice""; ""3.2.4 Guinea pigs""; ""3.3. Developmental and Reproductive Effects""; ""3.4. Genotoxicity""; ""3.5. Carcinogenicity""; ""3.6. Summary""""4. SPECIAL CONSIDERATIONS""; ""4.1. Metabolism and Disposition""; ""4.2. Mechanism of Toxicity""; ""4.3. Structure-Activity Relationships""; ""4.4. Other Relevant Information""; ""4.4.1. Susceptible Subpopulations""; ""4.4.2. Species Differences""; ""4.4.3. Concentration-Exposure Duration Relationship""; ""5. DATA ANALYSIS FOR AEGL-1""; ""5.1. Human Data Relevant to AEGL-1""; ""5.2. Animal Data Relevant to AEGL-1""; ""5.3. Derivation of AEGL-1""; ""6. DATA ANALYSIS FOR AEGL-2""; ""6.1. Human Data Relevant to AEGL-2""; ""6.2. Animal Data Relevant to AEGL-2""; ""6.3. Derivation of AEGL-2""""7. DATA ANALYSIS FOR AEGL-3""; ""7.1. Human Data Relevant to AEGL-3""; ""7.2. Animal Data Relevant to AEGL-3""; ""7.3. Derivation of AEGL-3""; ""8. SUMMARY OF AEGLS""; ""8.1. AEGL Values and Toxicity Endpoints""; ""8.2. Comparisons with Other Standards and Guidelines""; ""8.3. Data Adequacy and Research Needs""; ""9. REFERENCES""; ""2 Arsine1 Acute Exposure Guideline Levels""; ""SUMMARY""; ""1. INTRODUCTION""; ""2. HUMAN TOXICITY DATA""; ""2.1. Acute Lethality""; ""2.1.1. Case Reports""; ""2.2. Nonlethal Toxicity""; ""2.2.1. Case Reports""; ""2.2.2. Epidemiologic Studies""""2.3. Developmental and Reproductive Toxicity""; ""2.4. Genotoxicity""; ""2.5. Carcinogenicity""; ""2.6. Summary""; ""3. ANIMAL TOXICITY DATA""; ""3.1. Acute Lethality""; ""3.1.1. Nonhuman Primates""; ""3.1.2. Dogs""; ""3.1.3. Cats""; ""3.1.4 Rats""; ""3.1.5. Mice""; ""3.2. Nonlethal Toxicity""; ""3.2.1. Nonhuman Primates""; ""3.2.2. Rats""; ""3.2.3. Mice""; ""3.2.4. Hamsters""; ""3.3. Developmental/Reproductive Toxicity""; ""3.3.1. Rats""; ""3.3.2. Mice""; ""3.4. Genotoxicity""; ""3.5. Carcinogenicity""; ""3.6. Summary""; ""4. SPECIAL CONSIDERATIONS""; ""4.1. Metabolism and Disposition""