1.

Record Nr.

UNINA9910778274603321

Titolo

Applications of toxicogenomic technologies to predictive toxicology and risk assessment [[electronic resource] /] / Committee on Applications of Toxicogenomic Technologies to Predictive Toxicology ; Board on Environmental Studies and Toxicology ; Board on Life Studies ; Division on Earth and Life Studies ; National Research Council of the National Academies

Pubbl/distr/stampa

Washington, D.C., : National Academies Press, c2007

ISBN

0-309-17889-4

1-281-10990-8

9786611109905

0-309-11299-0

Descrizione fisica

1 online resource (299 p.)

Disciplina

616/.042

Soggetti

Genetic toxicology

DNA microarrays - Statistical methods

Health risk assessment

Carcinogenesis

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Bibliographic Level Mode of Issuance: Monograph

Nota di bibliografia

Includes bibliographical references.

Nota di contenuto

Introduction -- Toxicogenomic technologies -- Experimental design and data analysis -- Application to exposure assessment -- Application to hazard screening -- Application to analyzing variation in human susceptibility -- Application to the study of mechanisms of action -- Other potential applications of toxicogenomic technologies to risk assessment -- Validation -- Sample and data collection and analysis -- Ethical, legal, and social issues -- Conculsions and recommendations.