| |
|
|
|
|
|
|
|
|
1. |
Record Nr. |
UNINA9910778133403321 |
|
|
Autore |
Kielhorn J |
|
|
Titolo |
2-butenal [[electronic resource] /] / first draft prepared by J. Kielborn and I. Mangelsdorf ; and K. Ziegler-Skylakakis |
|
|
|
|
|
|
|
Pubbl/distr/stampa |
|
|
Geneva, : World Health Organization, c2008 |
|
|
|
|
|
|
|
ISBN |
|
1-282-25001-9 |
9786612250019 |
92-4-068367-4 |
|
|
|
|
|
|
|
|
Descrizione fisica |
|
1 online resource (55 p.) |
|
|
|
|
|
|
Collana |
|
Concise international chemical assessment document, , 1020-6167 ; ; 74 |
|
|
|
|
|
|
|
|
Altri autori (Persone) |
|
MangelsdorfI |
Ziegler-SkylakakisK |
|
|
|
|
|
|
|
|
Disciplina |
|
|
|
|
|
|
Soggetti |
|
Crotonaldehyde - Environmental aspects |
Crotonaldehyde - Toxicology |
Crotonaldehyde - Physiological effect |
|
|
|
|
|
|
|
|
Lingua di pubblicazione |
|
|
|
|
|
|
Formato |
Materiale a stampa |
|
|
|
|
|
Livello bibliografico |
Monografia |
|
|
|
|
|
Note generali |
|
"IPCS, International Programme on Chemical Safety." |
"Published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organization, and the World Health Organization, and produced within the framework of the Inter-Organization Programme for the Sound Management of Chemicals." |
|
|
|
|
|
|
|
|
Nota di bibliografia |
|
Includes bibliographical references (p. 32-38). |
|
|
|
|
|
|
Nota di contenuto |
|
COVER; COPYRIGHT; TABLE OF CONTENTS; FOREWORD; 1. EXECUTIVE SUMMARY; 2. IDENTITY AND PHYSICAL/CHEMICAL PROPERTIES; 3. ANALYTICAL METHODS; 4. SOURCES OF HUMAN AND ENVIRONMENTAL EXPOSURE; 5. ENVIRONMENTAL TRANSPORT, DISTRIBUTION, TRANSFORMATION, AND ACCUMULATION; 6. ENVIRONMENTAL LEVELS AND HUMAN EXPOSURE; 7. COMPARATIVE KINETICS AND METABOLISM IN LABORATORY ANIMALS AND HUMANS; 8. EFFECTS ON LABORATORY MAMMALS AND IN VITRO TEST SYSTEMS; 9. EFFECTS ON HUMANS; 10. EFFECTS ON OTHER ORGANISMS IN THE LABORATORY AND FIELD; 11. EFFECTS EVALUATION; 12. PREVIOUS EVALUATIONS BY IOMC BODIES; REFERENCES |
APPENDICES |
|
|
|
|
|
|
|
|
|
|
|
|
|
Sommario/riassunto |
|
2-Butenal (also known as crotonaldehyde) is an a,-unsaturated aldehyde and consequently a very reactive compound. It is a chemical intermediate used chiefly in the manufacture of sorbates, solvents, and, to a lesser extent, pharmaceutical products and aroma chemicals. This document studies the pharmacokinetics, environmental exposure, chemical toxicology and carcinogenicity of 2-butenal. However, to enable an understanding and evaluation of this aldehyde in the context of environmental health, other aldehydes, such as formaldehyde, acetaldehyde, and acrolein, are mentioned for comparison, where |
|
|
|
|
|
|
|
| |