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1. |
Record Nr. |
UNINA9910146399103321 |
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Titolo |
Aptamers in bioanalysis [[electronic resource] /] / edited by Marco Mascini |
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Pubbl/distr/stampa |
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Hoboken, NJ, : Wiley, c2009 |
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ISBN |
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1-282-11267-8 |
9786612112676 |
0-470-38077-2 |
0-470-38076-4 |
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Descrizione fisica |
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1 online resource (346 p.) |
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Classificazione |
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CHE 808f |
CHE 860f |
WC 4150 |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Oligonucleotides |
Biochemistry |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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APTAMERS IN BIOANALYSIS; CONTENTS; PREFACE; CONTRIBUTORS; I INTRODUCTION; 1 APTAMERS: LIGANDS FOR ALL REASONS; 1.1 Introduction; 1.2 The Power of Selection and Aptamer Refinement; 1.3 The Chemistry Drives the Shape; 1.4 Aptaregulators; 1.5 Aptasensors; 1.6 Prospects; References; 2 SELEX AND ITS RECENT OPTIMIZATIONS; 2.1 Introduction; 2.2 Aptamers and Their Selection by SELEX; 2.3 Modifications of SELEX Technology; 2.4 Advantages and Limitations of Aptamers and Their Selection Technology; 2.5 Applications of Aptamers Being Developed for the Market; 2.6 Future Perspectives; References |
II BIOSENSORS3 ELECTROCHEMICAL APTASENSORS; 3.1 Introduction; 3.2 Electrochemical Aptasensor Based on Redox-Active Aptamer Monolayers Linked to Electrodes; 3.3 Enzyme-Based Amplified Electrochemical Aptasensors; 3.4 Amplified Electrochemical Aptasensors Based on Nanoparticles; 3.5 Label-Free Electrochemical Aptasensors; 3.6 Field-Effect Transistor-Based Aptasensors; 3.7 Conclusions and Perspectives; References; 4 APTAMERS: HYBRIDS BETWEEN NATURE AND TECHNOLOGY; 4.1 Introduction; 4.2 Specific |
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Features of Aptamers; 4.3 Electrochemical Detection of Nucleic Acids |
4.4 Cytochrome c Binding by Aptamers4.5 DNA Machines and Aptamers; References; 5 DETECTION OF PROTEIN-APTAMER INTERACTIONS BY MEANS OF ELECTROCHEMICAL INDICATORS AND TRANSVERSE SHEAR MODE METHOD; 5.1 Introduction; 5.2 Immobilization of Aptamers on a Solid Support; 5.3 Detection of Aptamer-Ligand Interactions; 5.3.1 Electrochemical Methods; 5.3.2 Acoustic Methods; 5.4 Conclusions; References; 6 BIOSENSORS USING THE APTAMERIC ENZYME SUBUNIT: THE USE OF APTAMERS IN THE ALLOSTERIC CONTROL OF ENZYMES; 6.1 Aptamers as Molecular Recognition Elements of Biosensors |
6.1.1 Comparing Aptamers to Antibodies6.1.2 Signaling Aptamers; 6.2 Homogeneous Sensing; 6.2.1 Biosensor Systems That Do Not Require Bound-Free Separation; 6.2.2 Aptameric Enzyme Subunit; 6.3 Evolution-mimicking Algorithm for the Improvement of Aptamers; References; 7 NANOMATERIAL-BASED LABEL-FREE APTASENSORS; 7.1 Introduction; 7.2 Label-Free Electrochemical Aptasensors; 7.3 Field-Effect Transistor-Based Aptasensors; 7.4 Label-Free Aptasensors Based on Localized Surface Plasmon Resonance; 7.5 Forthcoming Challenges and Concluding Remarks; References |
8 APTAMER-BASED BIOANALYTICAL ASSAYS: AMPLIFICATION STRATEGIES8.1 Introduction; 8.2 Bioanalytical Assays Based on Aptamer-Functionalized Nanoparticles; 8.3 Aptamers and Quantum Dot-Based Assays; 8.4 Aptazymes and Aptamer-Based Machines; 8.5 Polymerase Chain Reaction as an Amplification Method in Aptamer-Based Assays; 8.6 Conclusions; References; III APPLICATIONS; 9 KINETIC CAPILLARY ELECTROPHORESIS FOR SELECTION, CHARACTERIZATION, AND ANALYTICAL UTILIZATION OF APTAMERS; 9.1 Introduction; 9.1.1 Kinetic Capillary Electrophoresis; 9.1.2 The Concept of NECEEM and ECEEM |
9.2 Selection of Aptamers Using KCE Methods for Partitioning and Affinity Control |
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Sommario/riassunto |
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This is the first book to detail bioanalytical technologies and methods that have been developed using aptamers in analytical, medical, environmental, and food science applications. After an introduction to aptamers, aptamer targets, and their general uses, it discusses different applications with particular attention to the comparison between aptamer-based biosensors and methods versus the corresponding immunosensors. Examples of aptamer-based diagnostic techniques include whole-cell protein profiling (proteomics) and medical diagnostics for the distinction of diseased versus healthy states. |
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2. |
Record Nr. |
UNINA9910777496403321 |
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Autore |
Jackson Howard <1945-> |
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Titolo |
Good grammar for students [[electronic resource] /] / Howard Jackson |
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Pubbl/distr/stampa |
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London, : SAGE, 2005 |
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London : , : SAGE, , 2005 |
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ISBN |
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9781412902037 |
9786611362157 |
1-281-36215-8 |
1-84860-084-4 |
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Descrizione fisica |
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1 online resource (165 p.) |
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Collana |
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SAGE essential study skills |
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Disciplina |
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Soggetti |
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English language - Grammar |
English language - Orthography and spelling |
English language - Punctuation |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references (p. [127]-136) and index. |
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Nota di contenuto |
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Cover; Contents; Introduction; 1 What Do WeMean by 'Grammar' -Good and Bad?; 2 Some Basic Terminology; 3 Matching the Bits; 4 Clauses - Main and Subordinate; 5 Sentence Arrangements; 6 Sentences into Texts; 7 Getting Your Point Across; 8 Why Can't I Rely on My Computer's Grammar checker?; 9 Spelling and Punctuation; 10 Where To Go for Further Information; Glossary; Index |
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Sommario/riassunto |
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Many students set out in further and higher education with little grounding in the skills required for academic writing. This practical guide will give students a command of grammar, spelling and punctuation, enabling them to improve the quality and accuracy of their writing. The book includes: - the basics of English grammar - how sentences are structured; - help with spelling and punctuation; - tips on avoiding the most common mistakes and pitfalls; - advice on how students can improve their writing in essays, reports and projects. The book is pac |
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