1.

Record Nr.

UNINA9910768467703321

Titolo

Left main coronary revascularization / / editor, Bernardo Cortese

Pubbl/distr/stampa

Cham, Switzerland : , : Springer, , [2022]

©2022

ISBN

9783031052651

9783031052644

Descrizione fisica

1 online resource (180 pages)

Disciplina

617.412

Soggetti

Coronary artery bypass

Myocardial revascularization

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references.

Nota di contenuto

Intro -- Foreword -- Preface -- References -- Contents -- 1: History of Left Main Revascularization -- 1.1  Introduction -- 1.2  The History of Left Main Stenosis -- 1.3  Overview of Early Trials in the Medical Management Era of LMCA Stenosis -- 1.4  Overview of Early Trials of Supporting CABG Superiority in LMCA Stenosis -- 1.5  Historical Background and Early Experience of LMCA PCI -- 1.6  Overview of Randomized Trials of LMCA PCI Using First Degeneration DES with/without BMS -- References -- 2: Historical Background of Left Main Stem Revascularization: A Step Further -- 2.1  Introduction of the Percutaneous Revascularization -- 2.2  The First-Generation DES Versus CABG for Unprotected LMCAD: Were Interventional Cardiologists Overconfident? -- 2.3  Tackling the Left Main Stem with the Second-Generation DES -- References -- 3: Anatomical and Pathophysiological Considerations on the Left Main Coronary Artery -- 3.1  Anatomy of the Left Main Coronary Artery -- 3.1.1  Normal Anatomy of the Left Main Coronary Artery -- 3.1.2  Anatomical Variations of the Left Main Coronary Artery -- 3.1.3  Histological Characteristics of the Left Main Coronary Artery -- 3.1.4  Normal Dimensions of the Left Main Coronary Artery -- 3.1.5  Anatomy of Distal Left Main Coronary Artery Bifurcation -- 3.2  Pathophysiology of the Left Main Coronary Artery -- 3.2.1  Prevalence of Left Main Coronary Artery Disease -- 3.2.2  Role



of Endothelial Shear Stress in LM Bifurcation -- 3.2.3  Left Main Plaque Distribution -- 3.2.4  The Medina Classification for Left Main Bifurcation Disease -- 3.2.5  Uncommon Causes of Left Main Coronary Artery Disease -- References -- 4: CABG Vs. PCI for Left Main Revascularization -- 4.1  Introduction -- 4.2  Current Evidence Comparing PCI to CABG for LMCAD -- 4.2.1  Real-World Evidence -- 4.2.2  Randomized Clinical Trials.

4.3  Guideline Recommendations on LMCAD Revascularization -- 4.4  Individualized Patient Approach -- 4.4.1  Predicted Surgical Risk -- 4.4.2  Anatomy of CAD -- 4.4.3  Completeness of Revascularization -- 4.4.4  Procedural Urgency -- 4.4.5  Clinical Characteristics -- 4.4.5.1  Diabetes Mellitus -- 4.4.5.2  Heart Failure with Reduced Ejection Fraction -- 4.4.5.3  Chronic Kidney Disease -- 4.4.5.4  Bleeding Risk -- 4.4.5.5  General Status of the Patient -- 4.5  Conclusions -- References -- 5: CABG Should Be the First Option for Left Main Disease: A Cardiac Surgeon's Perspective -- 5.1  Introduction -- 5.2  When PCI Is the Better Choice? -- 5.3  When Surgery Is the Better Choice? -- 5.4  Conclusions -- References -- 6: PCI Should Be the First Option for All Left Main Disease? An Interventional Cardiologist's Perspective -- 6.1  Introduction -- 6.2  Not all LMS Disease is the Same -- 6.3  The Evidence -- 6.4  Longer Term Outcomes PCI vs CABG -- 6.5  Limitations of Trials to Date -- 6.6  PCI Technique and Strategy -- 6.7  PCI in the Emergency Setting -- 6.8  Unanswered Questions -- 6.9  Conclusion -- References -- 7: Which Interventional Device for Left Main PCI? A Description of Available Stents -- 7.1  Introduction -- 7.1.1  Xience (Abbott Vascular, Santa Clara, CA, USA) -- 7.1.2  Xience Vs Synergy -- 7.1.3  Biomatrix ™ Stent -- 7.1.4  Resolute Onyx -- 7.1.5  Orsiro Sirolimus-Eluting Stent -- 7.1.6  Ultimaster™ Tansei™ Stent (Terumo Corporation, Tokyo, Japan) -- 7.1.7  Xposition S Sirolimus-Eluting Stent (Stentys, Paris, France) -- 7.1.8  Dedicated Bifurcation Stent -- 7.2  Conclusion -- References -- 8: Which Interventional Technique for Left Main PCI? -- 8.1  Introduction -- 8.2  What Is Special About the Left Main Stem? -- 8.3  Provisional Side Branch Stenting -- 8.4  Systematic Two-Stent Approach -- 8.5  Difficult Wire Access.

8.6  Role of Intracoronary Imaging -- 8.7  Role of Stent Enhancement -- 8.8  Role of Mentorship -- 8.9  Tips and Tricks -- 8.10  Conclusion -- References -- 9: Which Surgical Technique for Left Main Coronary Artery Bypass? A Mini-Invasive Approach -- 9.1  Introduction and History -- 9.2  Indications -- 9.3  Contraindications -- 9.4  Surgical Procedure -- 9.5  Outcomes and Comparison to Other Revascularization Strategies -- 9.6  Hybrid Coronary Revascularization -- 9.6.1  Timing of the HCR -- 9.6.2  HCR Outcomes -- 9.7  Conclusions -- References -- 10: Preoperative IVUS Assessment of the Left Main -- 10.1  Introduction -- 10.2  Intravascular Ultrasound (IVUS) Technology -- 10.3  The Role of IVUS in Pre-operative LMCA Assessment -- 10.3.1  Plaque Morphology at IVUS -- 10.3.2  IVUS-Based Indication for Treatment and Relationship with Functional Evaluation -- 10.3.3  IVUS-Guided LMCA Assessment: Impact on Therapeutic Strategies -- 10.4  IVUS-Guided LMCA PCI: Clinical Evidences -- 10.5  Conclusions -- References -- 11: Preoperative Functional Assessment of the Left Main and Postoperative Side Branch Evaluation -- 11.1  Left Main Anatomy and Atherosclerotic Process -- 11.2  Limitations of the Angiography for LMS Evaluation -- 11.3  FFR and iFR: Principles -- 11.4  Tips and Tricks for LM Functional Assessment -- 11.5  Assessment of the Distal LM Bifurcation Post PCI -- 11.6  Conclusions -- References -- 12: Is There a Role for OCT for Left Main Assessment Before and After PCI? -- 12.1  Introduction --



12.2  Left Main Stem Anatomy and Atherosclerotic Disease Distribution -- 12.3  Practical Tips and Tricks for Correct Assessment of Left Main by OCT -- 12.4  Use of OCT for the Definition of LM Disease and for the Assessment of Plaque Morphology -- 12.5  Use of OCT for the Guidance and Optimization of Left Main Bifurcation PCI -- 12.6  Conclusions -- References.

13: A Clinical Appraisal of Optical Coherence Tomography for Left Main Stem Intervention -- 13.1  Introduction -- 13.2  Role of Intravascular Imaging to Improve Clinical Outcomes in Left Main Intervention -- 13.3  Assessment of Intermediate Lesions in the Left Main Stem -- 13.4  Clinical Data Supporting the Use of OCT Over IVUS -- 13.5  Ongoing Clinical Studies for LM PCI with OCT Guidance -- 13.6  Optimizing the Use of OCT in the LM with a Non-stent-Based Approach -- 13.7  Future Perspective -- References -- 14: The Role of Intravascular Imaging for Post-procedural and Long-Term Evaluation of the Revascularized Left Main -- References -- 15: Follow-up of Left Main Patients Treated with PCI or CABG -- 15.1  Background -- 15.2  Incidence and Time Course of Adverse Events After LMCA Revascularization -- 15.3  Dual Antiplatelet Therapy Duration -- 15.4  Role of Non-invasive and Invasive Ischemia Testing After LMCA PCI -- 15.4.1  Myocardial Perfusion Imaging -- 15.4.2  Exercise Stress Testing -- 15.4.3  Stress Echocardiography -- 15.4.4  Coronary Computed Tomography Angiography -- 15.4.5  Invasive Coronary Angiogram -- 15.5  Conclusion -- References.