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Record Nr. |
UNINA9910768201003321 |
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Autore |
Savari Mohammad-Nabil |
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Titolo |
Theranostic Iron-Oxide Based Nanoplatforms in Oncology : Synthesis, Metabolism, and Toxicity for Simultaneous Imaging and Therapy / / by Mohammad-Nabil Savari, Ali Jabali |
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Pubbl/distr/stampa |
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Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 |
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ISBN |
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Edizione |
[1st ed. 2023.] |
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Descrizione fisica |
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1 online resource (416 pages) |
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Collana |
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Nanomedicine and Nanotoxicology, , 2194-0460 |
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Disciplina |
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Soggetti |
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Medical physics |
Cancer - Imaging |
Nanochemistry |
Nanotechnology |
Biophysics |
Medical Physics |
Cancer Imaging |
Nanoengineering |
Bioanalysis and Bioimaging |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references. |
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Nota di contenuto |
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Introduction -- Drug conjugation chemistry in iron oxide nanoparticles (IONPs) -- Superparamagnetic iron oxide nanoparticle (SPION) Synthesis -- Properties of Iron oxide nanoparticles (IONPs) -- Pharmacokinetics of IONPs -- Magnetic Nanoparticles in Stimuli-Responsive Drug Delivery Systems -- IONPs-based treatment methods -- Diagnosis -- Biosensing -- Bioassays Based on Magnetic Phenomena -- Cytotoxicity/toxicity -- Coatings -- Concluding remarks and future perspectives. |
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Sommario/riassunto |
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This book highlights the most efficient and latest ways to deal with cancer, focusing on IONPs. The book describes some well-designed surface modifications performed through several functional materials over the surface of IONPs, which results in the development of multifunctional IONPs-based delivery nanoplatforms by enhancing |
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solubility, stability, and avoiding side effects on healthy cells. Several types of stimuli-responsive IONPs-based strategies are also discussed. Owing to magnetic, structural, and thermal properties, IONPs themselves can be utilized for magnetic targeting, magnetic hyperthermia, and phototherapy. Significant advancements are presented in IONPs-based immunotherapy, radiotherapy, and sonodynamic therapy for the efficient treatment of cancer. Finally, the book presents RIONs which serve as the parent platform for the development of powerful DMCAs utilized in SPECT/MRI and PET/MRI applications. |
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