1.

Record Nr.

UNISA996390608003316

Autore

Walgrave William

Titolo

Decimal arithmetick [[electronic resource] ] : wherein the whole art is made easy to any indifferent capacity. By notation, addition, substraction, multiplication, and division. With several variations. Also, reduction, with the golden rule, or rule of three, shewing several wayes of measuring circles, globes, balls or cylinders, &c. and to find the solid content of any butt, pipe or cask cones and their frustums, with several waies of measuring taper timber. To which is added the description of a very easy instrument for the taking of any heights or distances without geometry or trigonometry, scale compasses or line of cords, only counting the divisions of the instrument, with the explanation of the multiplication of decimal or vulgar fractions, the rules of practise in decimals and so plain a way of extracting the square root almost as easy division. Also an essay to gunnery, shewing several waies of finding any inaccessible distance of altitude, within common sight, with very many things never before made publick, of which you m

Pubbl/distr/stampa

London, : printed for the author and are to be sold by him and the Two White posts in Newton street in St. Giles's, and Mr. Walter Hayes at the Cross Daggers in Moor-Fields, 1681

Descrizione fisica

[8], 203, [29] p., [11] leaves of plates (5 folded) : tables

Soggetti

Arithmetic

Mathematics

Mathematical instruments

Gunnery

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

With errata on p. [7].

Caption title on p. 103: An essay to gunnery.

Reproduction of the original in the British Library.

Sommario/riassunto

eebo-0018



2.

Record Nr.

UNINA9910768191303321

Titolo

Cancer Epigenetics / / edited by Rasime Kalkan

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023

ISBN

3-031-42365-8

Edizione

[1st ed. 2023.]

Descrizione fisica

1 online resource (389 pages)

Collana

Epigenetics and Human Health, , 2191-2270 ; ; 11

Disciplina

616.99/4042

Soggetti

Epigenetics

Cancer - Genetic aspects

Pharmaceutical chemistry

Cancer Genetics and Genomics

Medicinal Chemistry

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references.

Nota di contenuto

Part-1. Background -- Chapter 1. An Overview of Epigenetics Modifications in Normal and Cancer Cell -- Chapter 2. Epigenetic Enzymes and Mutation of Epigenetic Enzymes -- Chapter 3. Introduction to Cancer Epigenetics -- Part II. Cancer Specific Epigenetic Alterations -- Chapter 4. Epigenetics in the Diagnosis, Prognosis and Therapy of Cancer -- Chapter 5. The Clinical Studies and Epi-Drugs In Various Cancer Types -- Chapter 6. Epigenetic Regulation in Breast Cancer Tumor Microenvironment -- Chapter 7. The Epigenetics Of Brain Tumors: Fundamental Aspects Of Epigenetics In Glioma -- Chapter 8. Epigenetic Alterations in Pancreatic Cancer -- Chapter 9. Current Preclinical Applications of Pharmaco-Epigenetics in Cardiovascular Diseases -- Chapter 10. Epigenetic Alterations in Colorectal Cancer -- Chapter 11. Epigenetic Alterations in Hematopoietic Disorders.

Sommario/riassunto

Epigenetic alterations are heritable changes that play a key role in human development and tissue-specific gene expression patterns. These changes can lead to alterations involved in tumor formation, imprinting, and metabolic disorders. Recent advances can help us understand the importance of epigenetic changes in both cancer



development and tumor progression. In addition, epigenetic alterations may also be useful diagnostic and prognostic markers for the analysis of tumor progression. Split into two parts, the book opens with a comprehensive overview of the identification and analysis of epigenetic changes in cancer and the consequences of such changes during tumor development. The second part focusses on cancer specific epigenetic alterations and discusses the potential use of epigenetic markers as biomarkers in diagnosis, early cancer progression, and prognosis. Moreover, it reviews the therapeutic potential of epigenetic drugs. Given its scope, Cancer Epigenetics is an indispensable resource not only for researchers working in the field of human epigenetics and cancer research but also for advanced students seeking for an introduction into epigenetic mechanisms. .