1.

Record Nr.

UNINA9910765760803321

Titolo

Advances in Micro-Bioreactor Design for Organ Cell Studies / / edited by Carl-Fredrik Mandenius

Pubbl/distr/stampa

Basel : , : MDPI, , 2018

©2018

ISBN

3-03897-232-0

Descrizione fisica

1 online resource (vii, 157 pages) : illustrations

Collana

Bioengineering

Disciplina

660.6

Soggetti

Bioengineering

Bioreactors

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references.

Nota di contenuto

Carl-Fredrik Mandenius -- Clare Selden and Barry Fuller -- Claudia Kuhlbach, Sabrina da Luz, Frank Baganz, Volker C. Hass and Margareta M. Mueller -- Yi-Chin Toh, Anju Raja, Hanry Yu and Danny van Noort -- Ana C. Fernandes, Julia M. Halder, Bettina M. Nestl, Bernhard Hauer, Krist V. Gernaey and Ulrich Kruhne -- Krzysztof Wrzesinski and Stephen J. Fey -- Nora Freyer, Selina Greuel, Fanny Knospel, Florian Gerstmann, Lisa Storch, Georg Damm, Daniel Seehofer, Jennifer Foster Harris, Rashi Iyer, Frank Schubert and Katrin Zeilinger -- Jonas Christoffersson, Florian Meier, Henning Kempf, Kristin Schwanke, Michelle Coffee, Mario Beilmann, Robert Zweigerdt and Carl-Fredrik Mandenius -- Tannaz Tajsoleiman, Mohammad Jafar Abdekhodaie, Krist V. Gernaey and Ulrich Kruhne.

Sommario/riassunto

Micro-bioreactors offer unique opportunities to study biological systems under fluidic conditions. The concept of micro-bioreactors suggests that biological reaction conditions at a large scale can be scaled down to micro-volumes while maintaining performance and functionality. Models and operation principles can be simulated at a smaller scale, either by scaling down organs in the human body, or bioreactors for the production of biologics. This book highlights these issues with much focus on new engineering design approached. Initial chapters cover conceptual design of microbioreactors and organ-on-chips, and the role of microbioreactors in tissue engineering for the



clinical and for therapeutic targets. Two chapters are dedicated to microbioreactors for implementing tumour models. Other chapters discuss three-dimensional models for hepatic and cardiac cells for toxicity testing and drug evaluation. Finally, the design of organ chips for cartilage scaffolds and integration of sensors are covered in separate chapters. We believe the book have substantial value for researchers active in bioreactor engineering, drug development and cell physiology as well as readers interested in the these topics.

2.

Record Nr.

UNINA9911006580103321

Autore

Burton Terence T. <1950->

Titolo

Accelerating lean six sigma results : how to achieve improvement excellence in the new economy / / Terence T. Burton

Pubbl/distr/stampa

Fort Lauderdale, FL : , : J. Ross Publishing, , [2011]

©2011

ISBN

1-68015-168-1

1-60427-698-3

Edizione

[1st ed.]

Descrizione fisica

1 online resource (432 p.)

Disciplina

658.4/013

Soggetti

Total quality management

Cost effectiveness

Cost control

Six sigma (Quality control standard)

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Includes index.

Nota di contenuto

Improvement Excellence : the missing factor -- Scaleable improvement 2010 and beyond: rapid deployment and rapid results -- The accelerators of lean six sigma -- Accelerator #1: reset leadership, strategy, and vision -- Accelerator #2: robust deployment planning -- Accelerator #3: customized education and development -- Accelerator #4: communicate, communicate, communicate -- Accelerator #5: launching with the best in mind -- Accelerator #6: strong extensive mentoring support -- Accelerator #7: DMAIC the deployment process



regularly -- Accelerator #8: accelerate individual project paths -- Accelerator #9: complete the C in DMAIC -- Accelerator #10: practice concurrent continuous deployment -- Greatest opportunities: transactional enterprise process improvement -- The intersection of leadership, improvement, and technology.

Sommario/riassunto

In the new economy, the mandates for improvement initiatives are rapid deployment and sustainable results. Accelerating Lean Six Sigma Results provides real-world direction for this new improvement agenda with targeted rapid deployment and the Scalable Lean Six Sigma approach for quickly achieving high impact results, return on investment, and growth in global market share.