Immuno-Oncology Crosstalk and Metabolism / / edited by Muzafar Ahmad Macha, Ajaz Ahmad Bhat, Nissar Ahmad Wani

• Record Nr.: UNINA9910743228803321
• Pubbl/distr/stampa: Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2022
• ISBN: 9789811662263; 9811662266; 9789811662256; 9811662258
• Edizione: [1st ed. 2022.]
• Descrizione fisica: 1 online resource (223 pages)
• Collana: Biomedical and Life Sciences Series
• Disciplina: 616.99406
• Soggetti: Cancer; Tumors - Immunological aspects; Cancer - Treatment; Biochemistry; Metabolism; Cytology; Immunology; Cancer Biology; Cancer Microenvironment; Tumour Immunology; Cancer Therapy; Metabolic Pathways
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Nota di bibliografia: Includes bibliographical references.
• Nota di contenuto: 1 Cancer Metabolism and Aggressive Tumor Behaviour -- 2 Immune Cell Metabolism and Function -- 3 Cancer Cell Metabolism Effecting Immune function -- 4 Immune Cell Metabolites as Fuel for Cancer Cells -- 5 Immuno-Onco metabolism and Resistance to Therapy -- 6 Targeting Immuno-Onco metaolism in Cancers -- 7 Timing of the major metabolic switches in immune cell activation and differentiation during cancer development.
• Sommario/riassunto: This book discusses the novel metabolic cross-talk between immune and tumor cells in the tumor microenvironment that promotes their growth and progression. It also describes deregulated metabolism in cancer cells that promotes suppressive and cancer cell-favourable microenvironment. Further, the book provides novel insights on the metabolic changes in immune cells that promote tumor cell growth and survival. In turn, it also reviews the involvement of immuno-onco metabolic cross-talk in the development of resistance to chemo-radiation therapy (CRT) in tumor cells. Lastly, it also explores the potential of immuno-oncology metabolism as a therapeutic approach against tumor cells.