1.

Record Nr.

UNINA9910735781103321

Titolo

Optical Polarimetric Modalities for Biomedical Research / / edited by Nirmal Mazumder, Yury V. Kistenev, Ekaterina Borisova, Shama Prasada K

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023

ISBN

3-031-31852-8

Edizione

[1st ed. 2023.]

Descrizione fisica

1 online resource (455 pages)

Collana

Biological and Medical Physics, Biomedical Engineering, , 2197-5647

Disciplina

570.2823

Soggetti

Optics

Biology - Technique

Biophysics

Materials - Analysis

Materials - Microscopy

Applied Optics

Biophysical Methods

Materials Characterization Technique

Microscopy

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

PartI. Stokes Mueller based polarimetry -- Chapter1. Polarization imaging of optical anisotropy in soft tissues -- Chapter2. Polarization techniques in biological microscopy -- Chapter3. Stokes Mueller Matrix Polarimetry: Effective Parameters of Anisotropic Turbid Media - Theory and Application -- Chapter4. Mueller matrix imaging -- Chapter5. Biological imaging through optical Mueller-matrix scanning microscopy -- Chapter6. Mueller polarimetry for biomedical applications -- Chapter7. Scattering phase functions and polarimetric responses of selected bioparticles -- PartII. Nonlinear polarization microscopy -- Chapter8. Polarization resolved nonlinear optical microscopy -- Chapter9. Polarization-resolved SHG microscopy for biomedical applications -- Chapter10. Polarization-resolved second harmonic generation for tissue imaging -- PartIII. Applications of polarization



techniques -- Chapter11. An Introduction to Fundamentals of Cancer Biology -- Chapter12. Polarization enabled optical spectroscopy and microscopy techniques for cancer diagnosis -- Chapter13. Polarization Microscopy in Biomedical Applications -- Chapter14. Machine learning in tissue polarimetry. .

Sommario/riassunto

This book focuses on polarization microscopy, a powerful optical tool used to study anisotropic properties in biomolecules, and its enormous potential to improve diagnostic tools for various biomedical research. The interaction of polarized light with normal and abnormal regions of tissue reveals structural information associated with its pathological condition. Diagnosis using conventional microscopy can be time-consuming, as pathologists require an hour to freeze and stain tissue slices from suspected patients. In comparison, polarization microscopy more quickly distinguishes abnormal tissue and provides better microstructural information of samples, even in the absence of staining. This book provides a basic understanding of the properties of polarized light, a description of the polarization microscope, and a mathematical formalism of Mueller matrix polarimetry. The authors discuss various advanced linear and nonlinear optical techniques such as optical coherence tomography (OCT), reflectance and transmission spectroscopy, fluorescence, multiphoton excitation, second harmonic generation, Raman microscopy, and more. They explore the exciting potential of integrating polarimetry with these techniques for possible applications in different areas of biomedical research, as well as the associated challenges. Including the most recent developments on the topic, this book serves as a modern guide to polarization microscopy and advancements in its use in biomedical research.