1.

Record Nr.

UNINA9910733707703321

Titolo

Progress in the Chemistry of Organic Natural Products 107 / / edited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Jun'ichi Kobayashi, Yoshinori Asakawa, Ji-Kai Liu

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018

ISBN

3-319-93506-2

Edizione

[1st ed. 2018.]

Descrizione fisica

1 online resource (168 pages)

Collana

Progress in the Chemistry of Organic Natural Products, , 2192-4309 ; ; 107

Disciplina

547

Soggetti

Chemistry, Organic

Pharmaceutical chemistry

Medicinal chemistry

Organic Chemistry

Pharmaceutics

Medicinal Chemistry

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references.

Sommario/riassunto

The first review describes examples of very promising compounds discovered from plants acquired from Africa, Southeast Asia, the Americas, and the Caribbean region with potential anticancer activity. These include plant secondary metabolites of the diphyllin lignan, penta[b]benzofuran, triterpenoid, and tropane alkaloid types. The second review presents 40 more erythrinan alkaloids, which were either new or were missed out in the last major reviews, bringing to a total of 154 known erythrinan alkaloids known to date. The reported pharmacological activities of the new and known alkaloids showed a greater bias towards central nervous system and related activities. Other prominent activities reported were antifeedant or insecticidal, cytotoxicity/antiĀ­tumor/antiĀ­cancer/estrogenic, antiprotozoal, antiinflammatory, antioxidant, antifungal and antiviral activities.