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1. |
Record Nr. |
UNISA996392769403316 |
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Titolo |
By the King: a proclamation. James R [[electronic resource] ] : Whereas for remedy of the present scarcity of money in this our kingdom, and that our standing forces may be the better paid and subsisted, and that our subjects of this realm may be the better enabled to pay and discharge the taxes, . |
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Pubbl/distr/stampa |
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Dublin, : Printed by Andrew Crook and Samuel Helsham, assigns of Benjamin Tooke printer to the King's most Excellent Majesty; and are to be sold at His Majesties Printing-House on Ormonde-Key, and the Colledge-Arms in Castle-street., 1689 |
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Descrizione fisica |
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Soggetti |
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Money - Ireland |
Ireland History War of 1689-1691 Early works to 1800 |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Title from caption title and opening lines of text. |
The verso of the first sheet is blank. |
"Given at our court at our castle of Dublin this 27th day of June 1689. And in the fifth year of our reign." |
Copper and brass shillings and half-crowns are now made current. Cf. Steele. |
Arms 187. |
Reproduction of original in the British Library. |
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Sommario/riassunto |
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2. |
Record Nr. |
UNINA9910728396903321 |
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Autore |
Macheras P (Panos) |
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Titolo |
Advances in Pharmacokinetics and Pharmacodynamics / / edited by Panos Macheras |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
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ISBN |
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9783031295416 |
9783031295409 |
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Edizione |
[1st ed. 2023.] |
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Descrizione fisica |
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1 online resource (208 pages) |
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Collana |
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AAPS Introductions in the Pharmaceutical Sciences, , 2522-8358 ; ; 9 |
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Disciplina |
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Soggetti |
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Drug delivery systems |
Drugs - Design |
Pharmaceutical chemistry |
Metabolism |
Pharmacology |
Clinical biochemistry |
Drug Delivery |
Structure-Based Drug Design |
Pharmaceutics |
Medical Biochemistry |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Pharmacokinetics -- Chapter 1: Current status in PBPK modeling -- Chapter 2: Physiologically based biopharmaceutics modeling (PBBM) Application on Food Effect Assessment -- Chapter 3: Physiologically based finite time pharmacokinetic (PBFTPK) models: Inception and development -- Chapter 4: Physiologically based finite time pharmacokinetic (PBFTPK) models: Applications -- Pharmacodynamics -- Chapter 5: Pharmacokinetic – Pharmacodynamic Modelling and Simulation in Clinical Practice and Studies -- Chapter 6: On the Verge of Impossibility: Accounting for Variability Arising from Permutations of Comorbidities that Affect the Fate of Drugs in the Human Body -- Chapter 7: Impact of Clinical Pharmacology on the Modernization of Drug Development and Regulation. |
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Sommario/riassunto |
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This book provides a concise overview of recent advances in Pharmacokinetics (PK) and Pharmacodynamics (PD). The pharmacokinetics section covers the state of the art in Physiologically Based Pharmacokinetic (PBPK) modeling (Chapter 1) as well as the assessment of food effect on drug absorption using PBPK modeling (Chapter 2). Chapters 3 and 4 describe the recent development of Physiologically Based Finite Time Pharmacokinetic (PBFTPK) models and their applications to pharmacokinetic data. The pharmacodynamics section focuses on PK/PD modeling. Chapter 5 provides an overview of PK/PD modeling and simulation in clinical practice and studies. Chapter 6 deals with the subject/physiology variability issue encountered in PK/PD studies, while Chapter 7 reviews the influence of clinical pharmacology in the modernization of drug development and regulation. This book is an essential reference for pharmaceutical scientists. |
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