Gioblastoma : current evidence / / edited by Amit Agrawal, Daulat Singh Kunwar

• Record Nr.: UNINA9910727287303321
• Pubbl/distr/stampa: London : , : IntechOpen, , 2023
• ISBN: 1-80356-129-7
• Descrizione fisica: 1 online resource (222 pages)
• Disciplina: 616.99481
• Soggetti: Brain - Tumors; Brain - Cancer
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Nota di contenuto: 1. Glioblastoma in Elderly Population -- 2. Glioblastomas: Molecular Diagnosis and Pathology -- 3. Perspective Chapter: Glioblastoma of the Corpus Callosum -- 4. Canine Glioma as a Model for Human Glioblastoma -- 5. Systemic Treatment in Glioblastoma -- 6. Noncanonical (Non-R132H) IDH-Mutated Gliomas -- 7. New Approaches in the Treatment of Glioblastoma Multiforme -- 8. A Role for Cardiac Glycosides in GBM Therapy -- 9. Potential Role of Cancer Stem Cells in Glioblastoma: A Therapeutic Aspect -- 10. A Story of Immunization with Autologous IFN-γ Secreting Glioma Cells in Patients with Glioblastoma Multiforme is Safe and Prolongs Both Overall and Progress Free Survival -- 11. Potential of Lipid Based Nanodrug Carriers for Targeted Treatment of Glioblastoma: Recent Progress and Challenges Ahead -- 12. Glycan and Glycosylation as a Target for Treatment of Glioblastoma.
• Sommario/riassunto: Glioblastoma (GBM) is a common and aggressive brain cancer with features of necrosis and endothelial proliferation in the histopathologic examination. Its presentation and management depend on tumor location, size, grade, and underlying histopathological characteristics. GBM tumors have clinical features of increased intracranial pressure, focal neurological deficits, or seizures (generalized or partial) with rapid progression. This book discusses GBM and its diagnosis, treatment, and management.