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Record Nr. |
UNINA9910717420903321 |
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Autore |
Pan Haitao |
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Titolo |
Bayesian adaptive design for immunotherapy and targeted therapy / / by Haitao Pan, Ying Yuan |
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Pubbl/distr/stampa |
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Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 |
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ISBN |
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Edizione |
[First edition 2023.] |
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Descrizione fisica |
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1 online resource (XI, 262 p. 58 illus., 50 illus. in color.) : illustrations |
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Disciplina |
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Soggetti |
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Biometry |
Biostatistics |
Clinical Trial Protocols as Topic |
Adaptive Clinical Trials as Topic |
Bayes Theorem |
Immunoteràpia |
Dianes farmacològiques |
Assaigs clínics |
Estadística matemàtica |
Estadística bayesiana |
Llibres electrònics |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references. |
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Nota di contenuto |
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Introduction to Adaptive Design and Delayed Outcomes -- Basics of Bayesian Statistics -- Phase I Dose-finding Design -- Phase II Design for Interim Monitoring -- Phase I-II Dose-finding Design -- Drug Combination Trial Design -- Conclusion. |
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Sommario/riassunto |
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This book provides a comprehensive review of novel adaptive trial designs for targeted therapies and immunotherapies. This book covers a wide range of novel statistical designs for various clinical settings, including early phase dose-escalation study, proof-of-concept trials, and confirmatory studies with registrational. The book includes real-life examples and software to facilitate practitioners to learn and use the designs in practice. |
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