1.

Record Nr.

UNINA9910709540803321

Autore

Keller Robert R

Titolo

Workshop on reliability issues in nanomaterials / / Robert R. Keller, David T. Read, Roop Mahajan

Pubbl/distr/stampa

Gaithersburg, MD : , : U.S. Dept. of Commerce, National Institute of Standards and Technology, , 2007

Descrizione fisica

1 online resource

Collana

NIST special publication ; ; 1043

Altri autori (Persone)

KellerRobert R

MahajanRoop

ReadD. T

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

2007.

Contributed record: Metadata reviewed, not verified. Some fields updated by batch processes.

Title from PDF title page.

Nota di bibliografia

Includes bibliographical references.



2.

Record Nr.

UNINA9910298966703321

Autore

Xu Ying <1960->

Titolo

Cancer Bioinformatics / / by Ying Xu, Juan Cui, David Puett

Pubbl/distr/stampa

New York, NY : , : Springer New York : , : Imprint : Springer, , 2014

ISBN

1-4939-1381-6

Edizione

[1st ed. 2014.]

Descrizione fisica

1 online resource (386 p.)

Disciplina

004

570

570285

610

Soggetti

Bioinformatics

Cancer - Research

Systems biology

Medicine

Computational Biology/Bioinformatics

Cancer Research

Systems Biology

Biomedicine, general

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references at the end of each chapters and index.

Nota di contenuto

Basic cancer biology -- Omic data, information derivable and computational needs -- Cancer classification and molecular signature identification -- Understanding cancer at the genomic level -- Elucidation of cancer divers through comparative omic analyses -- Hyaluronic acid: A key facilitator of cancer evolution -- Multiple routes for survival: Understanding how cancer evades apoptosis -- Cancer development in competitive and hostile environments -- Cell proliferation from regulated to deregulated state via epigenomic responses -- Understanding cancer invasion and metastasis -- Cancer after metastasis: The second transformation -- Searching for cancer biomarkers in human body fluids -- In silico investigation of cancer using publicly available data -- Understanding cancer as an evolving



complex system: our perspective.

Sommario/riassunto

This book provides a framework for computational researchers studying the basics of cancer through comparative analyses of omic data. It discusses how key cancer pathways can be analyzed and discovered to derive new insights into the disease and identifies diagnostic and prognostic markers for cancer. Chapters explain the basic cancer biology and how cancer develops, including the many potential survival routes. The examination of gene-expression patterns uncovers commonalities across multiple cancers and specific characteristics of individual cancer types. The authors also treat cancer as an evolving complex system, explore future case studies, and summarize the essential online data sources. Cancer Bioinformatics is designed for practitioners and researchers working in cancer research and bioinformatics. It is also suitable as a secondary textbook for advanced-level students studying computer science, biostatistics or biomedicine.