1.

Record Nr.

UNINA9910143507703321

Titolo

Mechanisms and biological significance of pulsatile hormone release [[electronic resource]]

Pubbl/distr/stampa

Chichester, West Sussex, England ; ; New York, : Wiley, 2000

ISBN

1-280-27261-9

9786610272617

0-470-66825-3

0-470-87078-8

0-470-87079-6

Descrizione fisica

1 online resource (281 p.)

Collana

Novartis Foundation symposium ; ; 227

Disciplina

572

612.4/05

612.405

Soggetti

Hormones - Secretion

Biological rhythms - Molecular aspects

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

"Symposium on Mechanisms and Biological Significance of Pulsatile Hormone Secretion, held at the Novartis Foundation, London, 2-4 March 1999"--P. v.

Nota di bibliografia

Includes bibliographical references and indexes.

Nota di contenuto

MECHANISMS AND BIOLOGICAL SIGNIFICANCE OF PULSATILE HORMONE SECRETION; Contents; Participants; Introduction; Rhythmic transcription: the molecular basis of oscillatory melatonin synthesis; Discussion; The frequency encoding of pulsatility; Discussion; Timing-dependent modulation of insulin mitogenic versus metabolic signalling; Discussion; Growth hormone pulse-activated STAT5 signalling: a unique regulatory mechanism governing sexual dimorphism of liver gene expression; Discussion; Orderliness of hormone release; Discussion

Prediction and significance of the temporal pattern of hormone secretion in disease states Discussion; Therapeutic implications of circadian rhythms in cancer patients; Discussion; Pathophysiology of human circadian rhythms; Discussion; Nature of altered pulsatile



hormone release and neuroendocrine network signalling in human ageing: clinical studies of the somatotropic, gonadotropic, corticotropic and insulin axes; Discussion; Pulsatile insulin secretion; Discussion; Control of growth hormone (GH) release by GH secretagogues; Discussion

Pulsatile parathyroid hormone secretion in health and diseaseDiscussion; Significance of pulsatility in the HPA axis; Discussion; Closing remarks; Index of contributors; Subject index

Sommario/riassunto

This exciting book brings together an international and interdisciplinary group of experts to discuss the importance of pulsatile signalling in the induction of biological responses. Coverage includes the basic mechanisms involved in hormone pulsatility, the significance of pulsatility in normal and disease conditions, the relevance of circadian rhythms, changes with ageing, and detailed consideration of specific peptide hormone systems. This book includes contributions from professionals working in both basic and clinical research and reveals much new and exciting work in this area and promis

2.

Record Nr.

UNINA9910698487503321

Autore

Gootnick David

Titolo

Millennium Challenge Corporation [[electronic resource] ] : analysis of compact development and future obligations and current disbursements of compact assistance

Pubbl/distr/stampa

Washington, DC : , : U.S. Govt. Accountability Office, , [2008]

Descrizione fisica

25 pages : digital, PDF file

Soggetti

Economic assistance - Developing countries

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Title from title screen (viewed on May 6, 2008).

Author: David Gootnick.

"April 11, 2008."

Paper version available from: U.S. Govt. Accountability Office, 441 G St., NW, Rm. LM, Washington, D.C. 20548.

"GAO-08-577R."



Nota di bibliografia

Includes bibliographical references.