1.

Record Nr.

UNINA9910695362703321

Autore

Johnson Robert D (Robert David), <1974->

Titolo

Poppy seed consumption or opiate use [[electronic resource] ] : the determination of thebaine and opiates of abuse in postmortem fluids and tissues : final report / / Robert D. Johnson, Russell J. Lewis, Rachel A. Hattrup

Pubbl/distr/stampa

Washington, D.C. : , : U.S. Dept. of Transportation, Federal Aviation Administration, Office of Aerospace Medicine

[Ft. Belvoir, VA] : , : [Available through the Defense Technical Information Center]

Springfield, Va. : , : Available through the National Technical Information Service, , [2005]

Descrizione fisica

i, 12 pages : digital, PDF file

Altri autori (Persone)

LewisRussell J

HattrupRachel A

Soggetti

Aircraft accidents - Human factors

Narcotics - Analysis

Opioid peptides - Analysis

Thebaine - analysis

Autopsy - methods

Morphine Derivatives - analysis

Narcotics - analysis

Technical Report

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Title from PDF cover (viewed Aug. 18, 2006).

"June 2005."

"DOT/FAA/AM-05/11."

Nota di bibliografia

Includes bibliographical references (pages 6-7).

Sommario/riassunto

Thebaine is a naturally occurring opiate that is introduced into the body, along with morphine and codeine, following the consumption of poppy seeds. Scientific literature has clearly demonstrated the distinct possibility of a morphine and/or codeine positive due to poppy seed



consumption. The potential legal consequences of an opiate positive necessitates that laboratories, both drug testing and forensic, differentiate between an opiate positive due to morphine or codeine use and an opiate positive due to poppy seed consumption. Identification and quantitation of opiates in postmortem fluids and tissues are important aspects of forensic toxicology and may provide crucial information in determining the cause of impairment and/or death. This report describes a rapid, automated procedure for the single-step extraction and simultaneous determination of hydrocodone, dihydrocodeine, codeine, oxycodone, hydromorphone, 6-MAM, morphine, and thebaine in postmortem fluids and tissues using a Zymark RapidTrace automated solid-phase extraction (SPE) system and gas chromatography with mass spectrometry.