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1. |
Record Nr. |
UNINA9910688366303321 |
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Titolo |
Connective Tissue Disease : current state of the art / / edited by Akira Takeda |
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Pubbl/distr/stampa |
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London : , : IntechOpen, , 2020 |
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©2020 |
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Descrizione fisica |
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1 online resource (96 pages) |
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Disciplina |
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Soggetti |
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Connective tissues - Diseases |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Sommario/riassunto |
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Connective tissue diseases (CTDs) comprise a number of systemic autoimmune disorders and related conditions characterized by rheumatic manifestations, production of myriad autoantibodies, and varied immune-mediated organ injury. To achieve the best outcomes for patients, accurate evaluation has become critical, and thus advanced diagnostic and assessment modalities have been developed that have had a revolutionary impact in precise characterization of the disease conditions in CTDs. This book provides an in-depth look at the current state of CTDs, while also presenting an overview that is easily understandable to newcomers to the field. Chapters cover such conditions as rheumatoid arthritis, lupus, systemic sclerosis spectrum diseases, and spondyloarthritis, as well as the importance of physical activity and exercise training in the clinical course of CTDs. |
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2. |
Record Nr. |
UNINA9910816371803321 |
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Autore |
Kondrashov Alexey S. <1957-> |
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Titolo |
Crumbling genome / / Alexey S. Kondrashov |
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Pubbl/distr/stampa |
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Hoboken, New Jersey : , : Wiley Blackwell, , 2017 |
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©2017 |
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ISBN |
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1-118-95213-8 |
1-118-95212-X |
1-118-95214-6 |
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Descrizione fisica |
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1 online resource (282 pages) |
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Disciplina |
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Soggetti |
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Evolutionary genetics |
Mutation (Biology) |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references at the end of each chapters and index. |
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Nota di contenuto |
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Genotypes and phenotypes -- Mendelian inheritance and population genetics -- Complex traits and their inheritance -- Unavoidable mutation -- Struggle for fidelity -- Mutation rates -- Natural selection -- Functioning DNA and junk DNA -- It takes all the running you can do -- Phenomenon of imperfection -- Our imperfect fitness -- Our imperfect wellness -- Mutational pressure on our species -- Ethical issues -- What to do?. |
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