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1. |
Record Nr. |
UNINA9910688234703321 |
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Autore |
Nadia S. Parachin |
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Titolo |
New edge of antibiotic development : antimicrobial peptides and corresponding resistance / / topic editors: Nádia S. Parachin and Octavio L. Franco |
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Pubbl/distr/stampa |
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Frontiers Media SA, 2014 |
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France : , : Frontiers Media SA, , 2014 |
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ISBN |
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Descrizione fisica |
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1 online resource (144 pages) : illustrations (colour); digital file(s) |
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Collana |
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Frontiers Research Topics |
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Soggetti |
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Pharmacy, Therapeutics, & Pharmacology |
Health & Biological Sciences |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Bibliographic Level Mode of Issuance: Monograph |
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Nota di bibliografia |
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Includes bibliographical references. |
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Sommario/riassunto |
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Increased pathogen resistance to conventional drugs is partially due to increased numbers of immune-compromised patients, therefore the development of alternative antibiotic therapies able to circumvent this problem is one of the intriguing challenges of modern medicine. The discovery of antimicrobial peptides has been considered, in recent years, to be essential for the solution to infections caused by bacterial and fungal diseases, owing to their commonly observed and naturally occurring resistance against pathogens. In addition to the obvious antimicrobial activity commonly associated with membrane disruption, such peptides also have shown auxiliary activities such as immunomodulatory, anti-tumor and biofilm-disruption. Moreover, antibiotic peptides have been considered critical as therapeutic agents for the control of infectious bacterial diseases; the resistance to antibiotics has become a globally recognized public health problem. In most bacterial species, after exposing microorganisms to antibiotic peptides, several systems are affected such as energy and nitrogen metabolism regulation, glucan biosynthesis, amino acid, protein, and nucleotide synthesis, and, moreover, various proteins show a stress response. Despite some articles having been published about bacterial |
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resistance toward antimicrobial peptides, multiple gaps need to be filled in order to better understand this mechanism. In this view, this edition proposes the analyses of these unusual and interesting peptides and will provide a clearer understanding of such bacterial resistance towards AMPs. In summary, this proposal focuses on AMPs and their multiple activities as well as on AMP bacterial resistance, attracting several researchers from different areas. |
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2. |
Record Nr. |
UNINA9910795109803321 |
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Autore |
Gabriel Karl |
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Titolo |
Catholicism and Religious Freedom : Renewing the Church in the Second Vatican Council / Karl Gabriel, Christian Spieß, Katja Winkler |
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Pubbl/distr/stampa |
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Paderborn, : Brill | Schöningh, 2018 |
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ISBN |
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Edizione |
[1st ed.] |
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Descrizione fisica |
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Disciplina |
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Soggetti |
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1962-1965 |
Aufklärung |
Zweites Vatikanisches Konzil |
Zivilgesellschaft |
Werte |
Säkularisierung |
Religionsfreiheit |
Politik |
Gewalt |
Katholiken |
katholische Kirche |
Katholizismus |
Lehre |
Moderne |
Modernisierung |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Front Matter -- Copyright page / Karl Gabriel , Christian Spiess and Katja Winkler -- Foreword / José Casanova -- Introduction / Karl Gabriel , Christian Spiess and Katja Winkler -- Dignitatis humanae: Development of the Text / Karl Gabriel , Christian Spiess and Katja Winkler -- Modernity – Religion – Catholicism / Karl Gabriel , Christian Spiess and Katja Winkler -- Religious Freedom / Karl Gabriel , Christian Spiess and Katja Winkler -- Continuity – Change – Break? / Karl Gabriel , Christian Spiess and Katja Winkler -- Factors of Change / Karl Gabriel , Christian Spiess and Katja Winkler -- The Path to Recognizing Religious Freedom as a Two-stage Learning Process / Karl Gabriel , Christian Spiess and Katja Winkler -- Back Matter -- References / Karl Gabriel , Christian Spiess and Katja Winkler -- Acknowledgements / Karl Gabriel , Christian Spiess and Katja Winkler. |
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Sommario/riassunto |
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Just about fifty years ago, in its declaration on religious freedom at the Second Vatican Council, the Catholic Church programmatically dispensed with political coercion as a means of enforcing its claim to truth. This act of self-imposed restriction with regard to religious claims to truth is exceptional in the history of religions. It is still extremely difficult to explain even today how such a traditional institution as the Catholic Church could have altered its position so fundamentally. In this volume the authors dispute how the Church came to its position, what the reasons and motives were for its repositioning, what shape this process of change took, and the steps involved in the change: What were the characteristics, circumstances and dynamics of the path of Catholicism to recognizing religious freedom? |
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